2H-Indazoles are synthesized using copper-catalyzed, one-pot, three-component reactions of 2-bromobenzaldehydes, primary amines, and sodium azide. A copper catalyst plays the key role in the formation of C-N and N-N bonds. This method has a broad substrate scope with a high tolerance for a variety of functional groups.
2H-Indazoles are synthesized using n class="Chemical">copper-catalyzed, one-pot, three-component reactions of 2-bromobenzaldehydes, primary amines, and sodium azide. A copper catalyst plays the key role in the formation of C-N and N-N bonds. This method has a broad substrate scope with a high tolerance for a variety of functional groups.
Authors: Trevor V Nykaza; Tyler S Harrison; Avipsa Ghosh; Rachel A Putnik; Alexander T Radosevich Journal: J Am Chem Soc Date: 2017-05-10 Impact factor: 15.419
Authors: Jaime Pérez-Villanueva; Lilián Yépez-Mulia; Ignacio González-Sánchez; Juan Francisco Palacios-Espinosa; Olivia Soria-Arteche; Teresita Del Rosario Sainz-Espuñes; Marco A Cerbón; Karen Rodríguez-Villar; Ana Karina Rodríguez-Vicente; Miguel Cortés-Gines; Zeltzin Custodio-Galván; Dante B Estrada-Castro Journal: Molecules Date: 2017-10-31 Impact factor: 4.411