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Literature DB >> 21644516

Nanomaterials for X-ray imaging: gold nanoparticle enhancement of X-ray scatter imaging of hepatocellular carcinoma.

Danielle Rand¹, Vivian Ortiz, Yanan Liu, Zoltan Derdak, Jack R Wands, Milan Tatíček, Christoph Rose-Petruck.

Abstract

We present the development of a new imaging technique for the early diagnosis of hepatocellular carcinoma that utilizes surface-modified gold nanoparticles in combination with X-ray imaging. Tissues labeled with these electron-dense particles show enhanced X-ray scattering over normal tissues, distinguishing cells containing gold nanoparticles from cells without gold in X-ray scatter images. Our results suggest that this novel approach could enable the in vivo detection of tumors as small as a few millimeters in size.

Entities: Chemical Disease Species

Mesh：

Substances：
Gold

Year: 2011 PMID： 21644516 PMCID： PMC3138192 DOI： 10.1021/nl200858y

Source DB: PubMed Journal: Nano Lett ISSN： 1530-6984 Impact factor: 11.189

30 in total

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Authors: S F Hain; I Fogelman
Journal: Cancer J Date: 2004 Mar-Apr Impact factor: 3.360

2. Early detection of hepatocellular carcinoma by real-time ultrasonography. A prospective study.

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Journal: Cancer Date: 1985-08-01 Impact factor: 6.860

Review 3. Antibody-directed therapy for human hepatocellular carcinoma.

Authors: Leonhard Mohr; Andy Yeung; Costica Aloman; Dane Wittrup; Jack R Wands
Journal: Gastroenterology Date: 2004-11 Impact factor: 22.682

4. The use of gold nanoparticles to enhance radiotherapy in mice.

Authors: James F Hainfeld; Daniel N Slatkin; Henry M Smilowitz
Journal: Phys Med Biol Date: 2004-09-21 Impact factor: 3.609

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Authors: K Okuda
Journal: J Hepatol Date: 2000 Impact factor: 25.083

6. Radioimmunolocation of hepatic and pulmonary metastasis of human colon adenocarcinoma.

Authors: H Takahashi; R Carlson; M Ozturk; S Sun; P Motte; W Strauss; K J Isselbacher; J R Wands; D Shouval
Journal: Gastroenterology Date: 1989-05 Impact factor: 22.682

7. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance.

Authors: L R Hirsch; R J Stafford; J A Bankson; S R Sershen; B Rivera; R E Price; J D Hazle; N J Halas; J L West
Journal: Proc Natl Acad Sci U S A Date: 2003-11-03 Impact factor: 11.205

8. Establishment and characterization of a new human hepatocellular carcinoma cell line.

Authors: L He; K J Isselbacher; J R Wands; H M Goodman; C Shih; A Quaroni
Journal: In Vitro Date: 1984-06

Review 9. Hepatocellular carcinoma: paradigm of preventive oncology.

Authors: Thomas R O'Brien; Gregory Kirk; Mingdong Zhang
Journal: Cancer J Date: 2004 Mar-Apr Impact factor: 3.360

10. Rational design of cytophilic and cytophobic polyelectrolyte multilayer thin films.

Authors: Jonas D Mendelsohn; Sung Yun Yang; Jeri'Ann Hiller; Allon I Hochbaum; Michael F Rubner
Journal: Biomacromolecules Date: 2003 Jan-Feb Impact factor: 6.988

14 in total

1. X-ray spatial frequency heterodyne imaging of protein-based nanobubble contrast agents.

Authors: Danielle Rand; Masaki Uchida; Trevor Douglas; Christoph Rose-Petruck
Journal: Opt Express Date: 2014-09-22 Impact factor: 3.894

2. A highly sensitive x-ray imaging modality for hepatocellular carcinoma detection in vitro.

Authors: Danielle Rand; Edward G Walsh; Zoltan Derdak; Jack R Wands; Christoph Rose-Petruck
Journal: Phys Med Biol Date: 2015-01-05 Impact factor: 3.609

3. Motionless electromagnetic phase stepping versus mechanical phase stepping in x-ray phase-contrast imaging with a compact source.

Authors: Katherine J Harmon; Houxun Miao; Andrew A Gomella; Eric E Bennett; Barbara A Foster; Priya Bhandarkar; Han Wen
Journal: Phys Med Biol Date: 2015-03-24 Impact factor: 3.609

4. 'Living' PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities.

Authors: Hongwei Chen; Hayley Paholak; Masayuki Ito; Kanokwan Sansanaphongpricha; Wei Qian; Yong Che; Duxin Sun
Journal: Nanotechnology Date: 2013-08-12 Impact factor: 3.874