Literature DB >> 2164394

Dissecting the complexity of the nervous system by enhancer detection.

H J Bellen1, C Wilson, W J Gehring.   

Abstract

Enhancer detectors are DNA constructs which, when introduced into a eukaryotic genome, respond to nearby genomic transcriptional regulatory elements by means of a reporter gene, revealing the expression pattern of genes in their vicinity. Recent experiments in Drosophila suggest that enhancer detection is a powerful method to identify genes that are expressed in the nervous system. Since enhancer detectors allow a rapid molecular and genetic characterization of genes in their vicinity, the method will greatly facilitate the study of neural development and behavior.

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Year:  1990        PMID: 2164394     DOI: 10.1002/bies.950120502

Source DB:  PubMed          Journal:  Bioessays        ISSN: 0265-9247            Impact factor:   4.345


  7 in total

1.  The Drosophila couch potato gene: an essential gene required for normal adult behavior.

Authors:  H J Bellen; H Vaessin; E Bier; A Kolodkin; D D'Evelyn; S Kooyer; Y N Jan
Journal:  Genetics       Date:  1992-06       Impact factor: 4.562

Review 2.  Molecular correlates of neuronal specificity in the developing insect nervous system.

Authors:  H Reichert
Journal:  Mol Neurobiol       Date:  1993 Fall-Winter       Impact factor: 5.590

3.  Refinement of tools for targeted gene expression in Drosophila.

Authors:  Barret D Pfeiffer; Teri-T B Ngo; Karen L Hibbard; Christine Murphy; Arnim Jenett; James W Truman; Gerald M Rubin
Journal:  Genetics       Date:  2010-08-09       Impact factor: 4.562

4.  Interferons and interleukin 6 suppress phosphorylation of the retinoblastoma protein in growth-sensitive hematopoietic cells.

Authors:  D Resnitzky; N Tiefenbrun; H Berissi; A Kimchi
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

Review 5.  Insertional mutagenesis in transgenic mice.

Authors:  T Rijkers; A Peetz; U Rüther
Journal:  Transgenic Res       Date:  1994-07       Impact factor: 2.788

6.  New patterns of gene activity in plants detected using an Agrobacterium vector.

Authors:  A Goldsbrough; M Bevan
Journal:  Plant Mol Biol       Date:  1991-02       Impact factor: 4.076

7.  Enhancer trap infidelity in Drosophila optomotor-blind.

Authors:  Lisa R Mayer; Sören Diegelmann; Yasmin Abassi; Fred Eichinger; Gert O Pflugfelder
Journal:  Fly (Austin)       Date:  2013-03-21       Impact factor: 2.160

  7 in total

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