| Literature DB >> 2164394 |
H J Bellen1, C Wilson, W J Gehring.
Abstract
Enhancer detectors are DNA constructs which, when introduced into a eukaryotic genome, respond to nearby genomic transcriptional regulatory elements by means of a reporter gene, revealing the expression pattern of genes in their vicinity. Recent experiments in Drosophila suggest that enhancer detection is a powerful method to identify genes that are expressed in the nervous system. Since enhancer detectors allow a rapid molecular and genetic characterization of genes in their vicinity, the method will greatly facilitate the study of neural development and behavior.Entities:
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Year: 1990 PMID: 2164394 DOI: 10.1002/bies.950120502
Source DB: PubMed Journal: Bioessays ISSN: 0265-9247 Impact factor: 4.345