Literature DB >> 21643589

Stereoselective aza-Darzens reactions of tert-butanesulfinimines: convenient access to chiral aziridines.

Toni Moragas Solá1, Ian Churcher, William Lewis, Robert A Stockman.   

Abstract

Stereoselective synthesis of 2,3-di- and 2,2',3-tri-substituted aziridines in good yields and excellent diastereoselectivities are achieved through aza-Darzens reactions of a range of tert-butanesulfinyl aldimines and ketimines with ethyl bromoacetate.

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Year:  2011        PMID： 21643589     DOI： 10.1039/c1ob05561e

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Efficient Access to Chiral Trisubstituted Aziridines via Catalytic Enantioselective Aza-Darzens Reactions.

Authors:  Barry M Trost; Tanguy Saget; Chao-I Joey Hung
Journal:  Angew Chem Int Ed Engl       Date:  2017-01-23       Impact factor: 15.336

Review 2.  Applications of aryl-sulfinamides in the synthesis of N-heterocycles.

Authors:  Rose Mary Philip; G S Susan Treesa; Salim Saranya; Gopinathan Anilkumar
Journal:  RSC Adv       Date:  2021-06-08       Impact factor: 4.036

3.  Highly Efficient Darzens Reactions Mediated by Phosphazene Bases under Mild Conditions.

Authors:  Carmine Lops; Paolo Pengo; Lucia Pasquato
Journal:  ChemistryOpen       Date:  2022-10       Impact factor: 2.630
  3 in total

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