Highly specific detection of IL-8 protein using combination tapered fiber-optic biosensor dip-probe.

We are reporting detection of IL-8 in a mixed protein solution, using combination tapered fiber-optic biosensor (CTFOB) dip-probe. Sandwich immunoassay was used as the detection technique. The specificity of the sensor was established by using two types of negative control probes. It is demonstrated that with the help of these CTFOB dip-probe we could successfully detect IL-8 with high specificity in protein mixture. The lowest detected concentration of IL-8 was 150 pM.