Literature DB >> 21643485

Effects of chronic, heavy cannabis use on executive functions.

Rebecca D Crean1, Susan F Tapert, Arpi Minassian, Kai Macdonald, Natania A Crane, Barbara J Mason.   

Abstract

This case describes the clinical course of a cannabis-dependent individual entering a 12-week abstinence-based research program. The case illustrates the effects of chronic, heavy cannabis use on executive functions at three time points: 1) 24 hours of abstinence; 2) 4 weeks of abstinence; and 3) 12 weeks of abstinence. It is followed by discussions by two clinical psychologists and a psychiatrist. The findings described here have important clinical implications, as executive functions have a vital role in treatment participation and in sustaining recovery. It should be of particular interest to clinicians who work with people with cannabis use disorders.

Entities:  

Keywords:  cannabis; cognitive impairment; executive functions; marijuana; neuropsychological assessment

Mesh:

Substances:

Year:  2011        PMID: 21643485      PMCID: PMC3106308          DOI: 10.1097/ADM.0b013e31820cdd57

Source DB:  PubMed          Journal:  J Addict Med        ISSN: 1932-0620            Impact factor:   3.702


  31 in total

1.  Neuropsychological performance in long-term cannabis users.

Authors:  H G Pope; A J Gruber; J I Hudson; M A Huestis; D Yurgelun-Todd
Journal:  Arch Gen Psychiatry       Date:  2001-10

2.  Dose-related neurocognitive effects of marijuana use.

Authors:  K I Bolla; K Brown; D Eldreth; K Tate; J L Cadet
Journal:  Neurology       Date:  2002-11-12       Impact factor: 9.910

3.  Substance use and withdrawal: neuropsychological functioning over 8 years in youth.

Authors:  Susan F Tapert; Eric Granholm; Nathan G Leedy; Sandra A Brown
Journal:  J Int Neuropsychol Soc       Date:  2002-11       Impact factor: 2.892

4.  Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study.

Authors:  Igor Grant; Raul Gonzalez; Catherine L Carey; Loki Natarajan; Tanya Wolfson
Journal:  J Int Neuropsychol Soc       Date:  2003-07       Impact factor: 2.892

5.  The influence of recency of use on fMRI response during spatial working memory in adolescent marijuana users.

Authors:  Alecia Dager Schweinsburg; Brian C Schweinsburg; Krista Lisdahl Medina; Tim McQueeny; Sandra A Brown; Susan F Tapert
Journal:  J Psychoactive Drugs       Date:  2010-09

6.  Specific attentional dysfunction in adults following early start of cannabis use.

Authors:  H Ehrenreich; T Rinn; H J Kunert; M R Moeller; W Poser; L Schilling; G Gigerenzer; M R Hoehe
Journal:  Psychopharmacology (Berl)       Date:  1999-03       Impact factor: 4.530

7.  Marijuana abstinence effects in marijuana smokers maintained in their home environment.

Authors:  A J Budney; J R Hughes; B A Moore; P L Novy
Journal:  Arch Gen Psychiatry       Date:  2001-10

8.  Cerebellar hypoactivity in frequent marijuana users.

Authors:  R I Block; D S O'Leary; R D Hichwa; J C Augustinack; L L Ponto; M M Ghoneim; S Arndt; J C Ehrhardt; R R Hurtig; G L Watkins; J A Hall; P E Nathan; N C Andreasen
Journal:  Neuroreport       Date:  2000-03-20       Impact factor: 1.837

9.  Cognitive functioning of long-term heavy cannabis users seeking treatment.

Authors:  Nadia Solowij; Robert S Stephens; Roger A Roffman; Thomas Babor; Ronald Kadden; Michael Miller; Kenneth Christiansen; Bonnie McRee; Janice Vendetti
Journal:  JAMA       Date:  2002-03-06       Impact factor: 56.272

10.  Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers.

Authors:  T W Robbins; M James; A M Owen; B J Sahakian; L McInnes; P Rabbitt
Journal:  Dementia       Date:  1994 Sep-Oct
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  22 in total

1.  Alcohol Versus Cannabinoids: A Review of Their Opposite Neuro-Immunomodulatory Effects and Future Therapeutic Potentials.

Authors:  Madhavan P Nair; Gloria Figueroa; Gianna Casteleiro; Karla Muñoz; Marisela Agudelo
Journal:  J Alcohol Drug Depend       Date:  2015-01-23

2.  Substance Abuse, Hepatitis C, and Aging in HIV: Common Cofactors that Contribute to Neurobehavioral Disturbances.

Authors:  Randi Melissa Schuster; Raul Gonzalez
Journal:  Neurobehav HIV Med       Date:  2012-02-16

Review 3.  WHY NOT POT?: A Review of the Brain-based Risks of Cannabis.

Authors:  Kai MacDonald; Katherine Pappas
Journal:  Innov Clin Neurosci       Date:  2016-04-01

4.  Effects of morphine/CP55940 mixtures on an impulsive choice task in rhesus monkeys.

Authors:  Vanessa Minervini; Charles P France
Journal:  Behav Pharmacol       Date:  2018-02       Impact factor: 2.293

5.  Deficient Functioning of Frontostriatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth.

Authors:  Marilyn Cyr; Gregory Z Tau; Martine Fontaine; Frances R Levin; Rachel Marsh
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2018-10-31       Impact factor: 8.829

Review 6.  Medical cannabis for chronic pain: can it make a difference in pain management?

Authors:  Mari Kannan Maharajan; Yu Jing Yong; Hong Yang Yip; Sze Shee Woon; Kar Mon Yeap; Khai Yeng Yap; Shuen Chi Yip; Kai Xian Yap
Journal:  J Anesth       Date:  2019-09-18       Impact factor: 2.078

7.  Effects of Adolescent Cannabinoid Self-Administration in Rats on Addiction-Related Behaviors and Working Memory.

Authors:  Erin K Kirschmann; Michael W Pollock; Vidhya Nagarajan; Mary M Torregrossa
Journal:  Neuropsychopharmacology       Date:  2016-09-01       Impact factor: 7.853

8.  Persistent effects of chronic Δ9-THC exposure on motor impulsivity in rats.

Authors:  Cristina Irimia; Ilham Y Polis; David Stouffer; Loren H Parsons
Journal:  Psychopharmacology (Berl)       Date:  2015-04-30       Impact factor: 4.530

9.  Altered Corticolimbic Control of the Nucleus Accumbens by Long-term Δ9-Tetrahydrocannabinol Exposure.

Authors:  Eun-Kyung Hwang; Carl R Lupica
Journal:  Biol Psychiatry       Date:  2019-08-06       Impact factor: 13.382

10.  Δ(9)Tetrahydrocannabinol impairs reversal learning but not extra-dimensional shifts in rhesus macaques.

Authors:  M J Wright; S A Vandewater; L H Parsons; M A Taffe
Journal:  Neuroscience       Date:  2013-01-16       Impact factor: 3.590

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