Literature DB >> 21641481

The need for technologies to prevent bilirubin-induced neurologic dysfunction syndrome.

Vinod K Bhutani1, David K Stevenson.   

Abstract

Dramatic improvements in the overall socioeconomic conditions have yet to impact the unacceptably high maternal (approximately 1500 maternal deaths daily, worldwide) and neonatal morbidity and mortality (more than 10,000 deaths per daily 200,000 live-births, worldwide) in the developing nations. Thus, nations with emerging markets have unique health-societal needs. All infants require a safer transition from a birthing facility to home during the first week after birth and providing for a nurturing environment to prevent neonatal illnesses is integral to "good clinical practice." The unmonitored occurrence of severe hyperbilirubinemia and kernicterus are emblematic of a fractured maternal child healthcare system. The "know-do" gaps that span private versus public health care systems in the emerging markets have led us to conclude that building an interdisciplinary leadership approach to provide innovative strategies and affordable technologies will help bridge and access existing social barriers in the micro- and macro-health environments. Thus, unfettered access, global benchmarks, and culturally relevant strategies are dependent on evidence-based affordable technologies to successfully transform societal health care practices. Implementation of jaundice-related technologies should serve as a template for other affordable newborn health products.
Copyright © 2011. Published by Elsevier Inc.

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Year:  2011        PMID: 21641481     DOI: 10.1053/j.semperi.2011.02.002

Source DB:  PubMed          Journal:  Semin Perinatol        ISSN: 0146-0005            Impact factor:   3.300


  7 in total

1.  Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia.

Authors:  Andreia Barateiro; Shujuan Chen; Mei-Fei Yueh; Adelaide Fernandes; Helena Sofia Domingues; João Relvas; Olivier Barbier; Nghia Nguyen; Robert H Tukey; Dora Brites
Journal:  Mol Pharmacol       Date:  2015-10-19       Impact factor: 4.436

Review 2.  Bilirubin-Induced Audiologic Injury in Preterm Infants.

Authors:  Cristen Olds; John S Oghalai
Journal:  Clin Perinatol       Date:  2016-02-15       Impact factor: 3.430

Review 3.  Audiologic impairment associated with bilirubin-induced neurologic damage.

Authors:  Cristen Olds; John S Oghalai
Journal:  Semin Fetal Neonatal Med       Date:  2015-01-07       Impact factor: 3.926

4.  Chemoprevention of bilirubin encephalopathy with a nanoceutical agent.

Authors:  Aniruddha Adhikari; Vinod K Bhutani; Susmita Mondal; Monojit Das; Soumendra Darbar; Ria Ghosh; Nabarun Polley; Anjan Kumar Das; Siddhartha Sankar Bhattacharya; Debasish Pal; Asim Kumar Mallick; Samir Kumar Pal
Journal:  Pediatr Res       Date:  2022-07-06       Impact factor: 3.756

5.  Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors.

Authors:  Andreia Barateiro; Helena Sofia Domingues; Adelaide Fernandes; João Bettencourt Relvas; Dora Brites
Journal:  Mol Neurobiol       Date:  2013-08-28       Impact factor: 5.590

6.  Effects of Hyperbilirubinemia on Auditory Brainstem Response of Neonates Treated with Phototherapy.

Authors:  Negin Salehi; Fereshte Bagheri; Hamid Ramezani Farkhani
Journal:  Iran J Otorhinolaryngol       Date:  2016-01

Review 7.  Neonatal hyperbilirubinemia and Rhesus disease of the newborn: incidence and impairment estimates for 2010 at regional and global levels.

Authors:  Vinod K Bhutani; Alvin Zipursky; Hannah Blencowe; Rajesh Khanna; Michael Sgro; Finn Ebbesen; Jennifer Bell; Rintaro Mori; Tina M Slusher; Nahed Fahmy; Vinod K Paul; Lizhong Du; Angela A Okolo; Maria-Fernanda de Almeida; Bolajoko O Olusanya; Praveen Kumar; Simon Cousens; Joy E Lawn
Journal:  Pediatr Res       Date:  2013-12       Impact factor: 3.756

  7 in total

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