Literature DB >> 21637883

Fast and efficient microwave-assisted synthesis of functionalized peptoids via Ugi reactions.

Angélica de Fátima S Barreto1, Otilie E Vercillo, Mike A Birkett, John C Caulfield, Ludger A Wessjohann, Carlos Kleber Z Andrade.   

Abstract

A wide range of N-alkylglycines (peptoids) can be efficiently prepared via Ugi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest.

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Year:  2011        PMID： 21637883     DOI： 10.1039/c1ob05471f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  7 in total

1.  Synthesis of α-amino-1,3-dicarbonyl compounds via Ugi flow chemistry reaction: access to functionalized 1,2,3-triazoles.

Authors:  Stanley N S Vasconcelos; Evelin Fornari; Ignez Caracelli; Hélio A Stefani
Journal:  Mol Divers       Date:  2017-07-12       Impact factor: 2.943

2.  A methanol and protic ionic liquid Ugi multicomponent reaction path to cytotoxic α-phenylacetamido amides.

Authors:  Ahmed Al Otaibi; Fiona M Deane; Cecilia C Russell; Lacey Hizartzidis; Siobhann N McCluskey; Jennette A Sakoff; Adam McCluskey
Journal:  RSC Adv       Date:  2019-03-08       Impact factor: 4.036

3.  Synthesis of acylhydrazino-peptomers, a new class of peptidomimetics, by consecutive Ugi and hydrazino-Ugi reactions.

Authors:  Angélica de Fátima S Barreto; Veronica Alves Dos Santos; Carlos Kleber Z Andrade
Journal:  Beilstein J Org Chem       Date:  2016-12-27       Impact factor: 2.883

Review 4.  Recent Advances in the Synthesis of Peptoid Macrocycles.

Authors:  Alexandra M Webster; Steven L Cobb
Journal:  Chemistry       Date:  2018-02-21       Impact factor: 5.236

5.  A Mild, Fast, and Scalable Synthesis of Substituted α-Acyloxy Ketones via Multicomponent Reaction Using a Continuous Flow Approach.

Authors:  Carlos Eduardo M Salvador; Carlos Kleber Z Andrade
Journal:  Front Chem       Date:  2019-07-30       Impact factor: 5.221

6.  The multicomponent approach to N-methyl peptides: total synthesis of antibacterial (-)-viridic acid and analogues.

Authors:  Ricardo A W Neves Filho; Sebastian Stark; Bernhard Westermann; Ludger A Wessjohann
Journal:  Beilstein J Org Chem       Date:  2012-11-28       Impact factor: 2.883

7.  Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids.

Authors:  Angélica de Fátima S Barreto; Otilie E Vercillo; Ludger A Wessjohann; Carlos Kleber Z Andrade
Journal:  Beilstein J Org Chem       Date:  2014-05-05       Impact factor: 2.883
  7 in total

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