Literature DB >> 21633348

Wnt signalling escapes to cilia.

Rieko Ajima, Hiroshi Hamada.   

Abstract

The primary cilium is proposed to restrain the level of canonical Wnt signalling, but it was unknown how the cilium achieves this. β-catenin, a component of the canonical Wnt signalling pathway, is now shown to be sequestered to the cilium by the Wnt signalling modulator Jouberin (Jbn) to restrain Wnt responses.

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Year:  2011        PMID： 21633348     DOI： 10.1038/ncb0611-636

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

1.  Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia.

Authors:  Peng Huang; Alexander F Schier
Journal:  Development       Date:  2009-09       Impact factor: 6.868

Review 2.  The primary cilium: a signalling centre during vertebrate development.

Authors:  Sarah C Goetz; Kathryn V Anderson
Journal:  Nat Rev Genet       Date:  2010-05       Impact factor: 53.242

Review 3.  When cilia go bad: cilia defects and ciliopathies.

Authors:  Manfred Fliegauf; Thomas Benzing; Heymut Omran
Journal:  Nat Rev Mol Cell Biol       Date:  2007-11       Impact factor: 94.444

4.  Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP.

Authors:  John F Dishinger; Hooi Lynn Kee; Paul M Jenkins; Shuling Fan; Toby W Hurd; Jennetta W Hammond; Yen Nhu-Thi Truong; Ben Margolis; Jeffrey R Martens; Kristen J Verhey
Journal:  Nat Cell Biol       Date:  2010-06-06       Impact factor: 28.824

5.  Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy.

Authors:  Madeline A Lancaster; Carrie M Louie; Jennifer L Silhavy; Louis Sintasath; Marvalyn Decambre; Sanjay K Nigam; Karl Willert; Joseph G Gleeson
Journal:  Nat Med       Date:  2009-08-30       Impact factor: 53.440

6.  Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry.

Authors:  Sehyun Kim; Norann A Zaghloul; Ekaterina Bubenshchikova; Edwin C Oh; Susannah Rankin; Nicholas Katsanis; Tomoko Obara; Leonidas Tsiokas
Journal:  Nat Cell Biol       Date:  2011-03-13       Impact factor: 28.824

7.  The cilia protein IFT88 is required for spindle orientation in mitosis.

Authors:  Benedicte Delaval; Alison Bright; Nathan D Lawson; Stephen Doxsey
Journal:  Nat Cell Biol       Date:  2011-03-27       Impact factor: 28.824

8.  Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors.

Authors:  Aiqun Li; Masaki Saito; Jen-Zen Chuang; Yun-Yu Tseng; Carlos Dedesma; Kazuhito Tomizawa; Taku Kaitsuka; Ching-Hwa Sung
Journal:  Nat Cell Biol       Date:  2011-03-13       Impact factor: 28.824

9.  Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo.

Authors:  Polloneal Jymmiel R Ocbina; Miquel Tuson; Kathryn V Anderson
Journal:  PLoS One       Date:  2009-08-31       Impact factor: 3.240

10.  Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease.

Authors:  Julie A Jonassen; Jovenal San Agustin; John A Follit; Gregory J Pazour
Journal:  J Cell Biol       Date:  2008-11-03       Impact factor: 10.539
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  7 in total

Review 1.  The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies.

Authors:  Junmin Pan; Tamina Seeger-Nukpezah; Erica A Golemis
Journal:  Cell Mol Life Sci       Date:  2012-07-11       Impact factor: 9.261

2.  nlz1 is required for cilia formation in zebrafish embryogenesis.

Authors:  Sunit Dutta; Shahila Sriskanda; Elangovan Boobalan; Ramakrishna P Alur; Abdel Elkahloun; Brian P Brooks
Journal:  Dev Biol       Date:  2015-08-29       Impact factor: 3.582

Review 3.  Aquatic models of human ciliary diseases.

Authors:  Mark E Corkins; Vanja Krneta-Stankic; Malgorzata Kloc; Rachel K Miller
Journal:  Genesis       Date:  2021-01-26       Impact factor: 2.487

4.  Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling.

Authors:  Camille Enjolras; Joëlle Thomas; Brigitte Chhin; Elisabeth Cortier; Jean-Luc Duteyrat; Fabien Soulavie; Maurice J Kernan; Anne Laurençon; Bénédicte Durand
Journal:  J Cell Biol       Date:  2012-04-16       Impact factor: 10.539

5.  BBS4 is necessary for ciliary localization of TrkB receptor and activation by BDNF.

Authors:  Carmen C Leitch; Norann A Zaghloul
Journal:  PLoS One       Date:  2014-05-27       Impact factor: 3.240

6.  Genetic screening reveals a link between Wnt signaling and antitubulin drugs.

Authors:  A H Khan; J S Bloom; E Faridmoayer; D J Smith
Journal:  Pharmacogenomics J       Date:  2015-07-07       Impact factor: 3.550

7.  Mutations in Alström protein impair terminal differentiation of cardiomyocytes.

Authors:  Lincoln T Shenje; Peter Andersen; Marc K Halushka; Cecillia Lui; Laviel Fernandez; Gayle B Collin; Nuria Amat-Alarcon; Wendy Meschino; Ernest Cutz; Kenneth Chang; Raluca Yonescu; Denise A S Batista; Yan Chen; Stephen Chelko; Jane E Crosson; Janet Scheel; Luca Vricella; Brian D Craig; Beth A Marosy; David W Mohr; Kurt N Hetrick; Jane M Romm; Alan F Scott; David Valle; Jürgen K Naggert; Chulan Kwon; Kimberly F Doheny; Daniel P Judge
Journal:  Nat Commun       Date:  2014-03-04       Impact factor: 14.919
  7 in total

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