Literature DB >> 21632969

Gynaecological symptoms reported by young women: examining the potential for earlier diagnosis of cervical cancer.

Sally Stapley1, William Hamilton.   

Abstract

BACKGROUND: Cervical cancer occurs at a younger age than most adult cancers. A pre-malignant stage can be identified at screening and treated. Screening begins at the age of 25 years in England, so in women younger than this, and in those who decline screening, cervical cancer can only be identified with symptoms. Aim. To identify the frequency of attendance for gynaecological conditions by young English women.
DESIGN: Historical cohort study using electronic primary care records.
METHODS: A cohort of English women aged 15-29 years was prepared from the General Practice Research Database. All gynaecological consultations were identified and collated. Frequencies of gynaecological consultation were analysed in three age bands: 15-19, 20-24 and 25-29 years and by calendar year.
RESULTS: The number of women available for study for each year ranged from 32 968 to 45 807. The percentage of women having any gynaecological consultation increased from 17.7% to 33.3% over the 7 years. If contraception is excluded, the percentages are 11.3% in 2003, rising to 20.1% in 2009. The rise in consultations occurred in all age bands and across most symptom categories. Post-coital bleeding and inter-menstrual bleeding-the two classic presentations of cervical cancer-were reported by 0.5% and 1.6% of women in 2009.
CONCLUSIONS: Gynaecological complaints are frequent in primary care, though the symptoms of possible cervical cancer only represent a small minority of the total. Although the chance of cancer in young women with abnormal vaginal bleeding is very small, visualization of the cervix is appropriate.

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Year:  2011        PMID: 21632969     DOI: 10.1093/fampra/cmr033

Source DB:  PubMed          Journal:  Fam Pract        ISSN: 0263-2136            Impact factor:   2.267


  14 in total

Review 1.  Performance characteristics of visualising the cervix in symptomatic young females: a review of primary care records in females with and without cervical cancer.

Authors:  Anita Wey Wey Lim; Willie Hamilton; Antony Hollingworth; Sally Stapley; Peter Sasieni
Journal:  Br J Gen Pract       Date:  2016-02-07       Impact factor: 5.386

2.  Prevalence Oncogenic Human Papillomavirus in Cervical Cancer Patients in Riau Province Indonesia.

Authors:  Maya Savira; Donel Suhaimi; Andani Eka Putra; Yusrawati Yusrawati; Nur Indrawati Lipoeto
Journal:  Rep Biochem Mol Biol       Date:  2022-01

3.  Experience of symptoms indicative of gynaecological cancers in UK women.

Authors:  E L Low; A E Simon; J Waller; J Wardle; U Menon
Journal:  Br J Cancer       Date:  2013-07-23       Impact factor: 7.640

4.  Delays in diagnosis of young females with symptomatic cervical cancer in England: an interview-based study.

Authors:  Anita W Lim; Amanda J Ramirez; William Hamilton; Peter Sasieni; Julietta Patnick; Lindsay Jl Forbes
Journal:  Br J Gen Pract       Date:  2014-10       Impact factor: 5.386

5.  Cytology in the diagnosis of cervical cancer in symptomatic young women: a retrospective review.

Authors:  Anita Ww Lim; Rebecca Landy; Alejandra Castanon; Antony Hollingworth; Willie Hamilton; Nick Dudding; Peter Sasieni
Journal:  Br J Gen Pract       Date:  2016-10-24       Impact factor: 5.386

6.  Recognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags, and Referrals.

Authors:  Garth Funston; Helena O'Flynn; Neil A J Ryan; Willie Hamilton; Emma J Crosbie
Journal:  Adv Ther       Date:  2018-03-07       Impact factor: 3.845

Review 7.  Anti-tumor activities of probiotics in cervical cancer.

Authors:  Moghaddaseh Jahanshahi; Parisa Maleki Dana; Bita Badehnoosh; Zatollah Asemi; Jamal Hallajzadeh; Mohammad Ali Mansournia; Bahman Yousefi; Bahram Moazzami; Shahla Chaichian
Journal:  J Ovarian Res       Date:  2020-06-11       Impact factor: 4.234

8.  Diagnosis of advanced cervical cancer, missed opportunities?

Authors:  Jérémie Mattern; Irène Letendre; Jeanne Sibiude; Cécile Pénager; Asma Jnifen; Fatoumata Souare; Sophie Ayel; Thuy Nguyen; Laurent Mandelbrot
Journal:  BMC Womens Health       Date:  2022-03-30       Impact factor: 2.809

9.  Measuring the nature and duration of symptoms of cervical cancer in young women: developing an interview-based approach.

Authors:  Anita W W Lim; Lindsay J L Forbes; Adam N Rosenthal; Kantipati S Raju; Amanda-Jane Ramirez
Journal:  BMC Womens Health       Date:  2013-11-13       Impact factor: 2.809

10.  Quantitative evaluation of an information leaflet to increase prompt help-seeking for gynaecological cancer symptoms.

Authors:  Melanie Morris; Claire Friedemann Smith; Emily Boxell; Jane Wardle; Alice Simon; Jo Waller
Journal:  BMC Public Health       Date:  2016-05-04       Impact factor: 3.295

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