Literature DB >> 21632888

Clinical significance of interleukin-2/gamma interferon ratios in Mycobacterium tuberculosis-specific T-cell signatures.

Franziska Suter-Riniker1, Antonia Berger, Désirée Mayor, Pascal Bittel, Patricia Iseli, Thomas Bodmer.   

Abstract

The simultaneous determination of interleukin-2 (IL-2) and gamma interferon (IFN-γ) in QuantiFERON-TB test plasma supernatants permitted the detection of shifts in Mycobacterium tuberculosis-specific T-cell signatures. A subset of the 84 subjects tested revealed a significantly elevated IL-2/IFN-γ ratio, which may be a marker for the successful elimination of M. tuberculosis infection.

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Year:  2011        PMID： 21632888      PMCID： PMC3147354          DOI： 10.1128/CVI.05013-11

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  12 in total

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