Literature DB >> 2163043

Changes in Na+,K(+)-ATPase, Ca2(+)-ATPase and some soluble enzymes related to energy metabolism in brains of patients with Alzheimer's disease.

G Liguri1, N Taddei, P Nassi, S Latorraca, C Nediani, S Sorbi.   

Abstract

Hexokinase, lactate dehydrogenase, acylphosphatase, (Na+,K+)-ATPase and Ca2(+)-ATPase of selected areas from postmortem Alzheimer's disease brains were studied. Hexokinase and lactate dehydrogenase were significantly changed in all the examined subcortical nuclei. (Na+,K+)-ATPase activity was altered in several areas of Alzheimer's disease brains. No changes in Ca2(+)-ATPase and acylphosphatase were observed. The main alterations of the assayed enzymes were observed in subcortical areas but not in cortical areas of Alzheimer's disease brains.

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Year:  1990        PMID: 2163043     DOI: 10.1016/0304-3940(90)90227-z

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  22 in total

1.  Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.

Authors:  Changxuan Liu; Yan Bai; Yiliang Chen; Yu Wang; Yoann Sottejeau; Lijun Liu; Xiaomei Li; Jerry B Lingrel; Deepak Malhotra; Christopher J Cooper; Joseph I Shapiro; Zi-jian Xie; Jiang Tian
Journal:  J Biol Chem       Date:  2012-03-27       Impact factor: 5.157

2.  Na,K-ATPase mRNA levels and plaque load in Alzheimer's disease.

Authors:  N B Chauhan; J M Lee; G J Siegel
Journal:  J Mol Neurosci       Date:  1997-12       Impact factor: 3.444

3.  Synergistic Toxicity of the Neurometabolites Quinolinic Acid and Homocysteine in Cortical Neurons and Astrocytes: Implications in Alzheimer's Disease.

Authors:  Paula Pierozan; Helena Biasibetti-Brendler; Felipe Schmitz; Fernanda Ferreira; Carlos Alexandre Netto; Angela T S Wyse
Journal:  Neurotox Res       Date:  2017-11-09       Impact factor: 3.911

4.  Bioenergetics breakdown in Alzheimer's disease: targets for new therapies.

Authors:  Uday Saxena
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2010-06-12

Review 5.  Is ammonia a pathogenetic factor in Alzheimer's disease?

Authors:  N Seiler
Journal:  Neurochem Res       Date:  1993-03       Impact factor: 3.996

6.  Chaperone-like manner of human neuronal tau towards lactate dehydrogenase.

Authors:  Rui Tian; Chun-Lai Nie; Rong-Qiao He
Journal:  Neurochem Res       Date:  2004-10       Impact factor: 3.996

Review 7.  Glial Na(+) -dependent ion transporters in pathophysiological conditions.

Authors:  Francesca Boscia; Gulnaz Begum; Giuseppe Pignataro; Rossana Sirabella; Ornella Cuomo; Antonella Casamassa; Dandan Sun; Lucio Annunziato
Journal:  Glia       Date:  2016-07-26       Impact factor: 7.452

8.  Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly.

Authors:  Takayuki Ohnishi; Masako Yanazawa; Tomoya Sasahara; Yasuki Kitamura; Hidekazu Hiroaki; Yugo Fukazawa; Isao Kii; Takashi Nishiyama; Akiyoshi Kakita; Hiroyuki Takeda; Akihide Takeuchi; Yoshie Arai; Akane Ito; Hitomi Komura; Hajime Hirao; Kaori Satomura; Masafumi Inoue; Shin-ichi Muramatsu; Ko Matsui; Mari Tada; Michio Sato; Eri Saijo; Yoshiki Shigemitsu; Satoko Sakai; Yoshitaka Umetsu; Natsuko Goda; Naomi Takino; Hitoshi Takahashi; Masatoshi Hagiwara; Tatsuya Sawasaki; Genji Iwasaki; Yu Nakamura; Yo-ichi Nabeshima; David B Teplow; Minako Hoshi
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-29       Impact factor: 11.205

9.  Soluble Amyloid Precursor Protein Alpha Interacts with alpha3-Na, K-ATPAse to Induce Axonal Outgrowth but Not Neuroprotection: Evidence for Distinct Mechanisms Underlying these Properties.

Authors:  Emilie Dorard; Stéphanie Chasseigneaux; Lucie Gorisse-Hussonnois; Cédric Broussard; Thierry Pillot; Bernadette Allinquant
Journal:  Mol Neurobiol       Date:  2017-10-05       Impact factor: 5.590

10.  Influence of Nitric Oxide-Cyclic GMP and Oxidative STRESS on Amyloid-β Peptide Induced Decrease of Na,K-ATPase Activity in Rat Hippocampal Slices.

Authors:  E M Kawamoto; M M Cararo-Lopes; P F Kinoshita; L E M Quintas; L S Lima; D Z Andreotti; C Scavone
Journal:  J Membr Biol       Date:  2021-07-29       Impact factor: 1.843

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