| Literature DB >> 21629640 |
Ramanath Mahale1, Pankaj Rathi, Chetan Ginegiri, Rajiv Aggarwal.
Abstract
Factor VII deficiency is a rare congenital coagulopathy. Prolonged prothrombin time with normal partial thromboplastin time indicates factor VII deficiency. For the definitive diagnosis, the specific factor VII level should be investigated. We report a 20 day old, baby girl, born full-term who was admitted with the diagnosis of sepsis. Hematological tests revealed prolonged prothrombin time and a factor VII level of nine percent. After antibiotic therapy and fresh frozen plasma replacement, her clinical status improved but the prothrombin time continued to be prolonged. On the seventh day of discharge the baby died due to sudden intracranial hemorrhage.Entities:
Keywords: Congenital coagulopathy; Factor VII deficiency; Intracranial hemorrhage
Year: 2010 PMID: 21629640 PMCID: PMC3002068 DOI: 10.1007/s12288-010-0023-5
Source DB: PubMed Journal: Indian J Hematol Blood Transfus ISSN: 0971-4502 Impact factor: 0.900