Literature DB >> 21627066

Concise total synthesis of calothrixins A and B.

Takumi Abe1, Toshiaki Ikeda, Reiko Yanada, Minoru Ishikura.   

Abstract

The concise total synthesis of calothrixins A and B has been accomplished by utilizing the one-pot formation of hexatriene as a key intermediate via the palladium-catalyzed tandem cyclization/cross-coupling reaction of triethyl(indol-2-yl)borate. In another key transformation, the indolo[3,2-j]phenanthridine core was prepared in high yield via Cu(I)-mediated 6π-electrocyclization.

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Year:  2011        PMID： 21627066     DOI： 10.1021/ol201107a

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.

Authors:  Su Xu; Thao Nguyen; Irene Pomilio; Maria C Vitale; Sadanandan E Velu
Journal:  Tetrahedron       Date:  2014-09-02       Impact factor: 2.457

2.  Ynamide carbopalladation: a flexible route to mono-, bi- and tricyclic azacycles.

Authors:  Craig D Campbell; Rebecca L Greenaway; Oliver T Holton; P Ross Walker; Helen A Chapman; C Adam Russell; Greg Carr; Amber L Thomson; Edward A Anderson
Journal:  Chemistry       Date:  2015-07-16       Impact factor: 5.236

3.  Total synthesis of pyrano[3,2-e]indole alkaloid fontanesine B by a double cyclization strategy.

Authors:  Tomoki Itoh; Yuusuke Chiba; Shunsuke Kawaguchi; Yuki Koitaya; Yuuma Yoneta; Koji Yamada; Takumi Abe
Journal:  RSC Adv       Date:  2019-04-03       Impact factor: 4.036

Review 4.  Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation.

Authors:  Su Xu; Bhavitavya Nijampatnam; Shilpa Dutta; Sadanandan E Velu
Journal:  Mar Drugs       Date:  2016-01-12       Impact factor: 5.118
  4 in total

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