BACKGROUND: Several studies have found that low grip strength is associated with dementia in Western populations. However, there have been few studies in Asian populations. This cross-sectional study aimed to examine whether grip strength is independently associated with dementia after controlling for other related factors in a Korean older population. METHODS: One thousand thirty-eight community-dwelling older people aged 65 or over within a defined geographic area were screened for dementia. Data on grip strength, sit-to-stand score, body mass index (BMI), socio-demographic factors (age, gender, marital status, education), and medical conditions (diabetes, hypertension, heart disease, stroke) were collected. Dementia was diagnosed with the 10/66 dementia diagnostic algorithm. RESULTS: Eleven percent of the participants were found to have dementia. After adjustment for other factors, grip strength (per 8-kg decrease) was independently associated with dementia (odds ratio, 1.59; 95% confidence interval, 1.19-2.14). Adjusted grip strength by BMI interaction terms showed marginal significance (p = 0.098); that is, older people with both reduced grip strength and low BMI were likely to be at higher risk for dementia. CONCLUSIONS: Reduced grip strength was independently associated with dementia in a Korean older population. This association was partially influenced by BMI.
BACKGROUND: Several studies have found that low grip strength is associated with dementia in Western populations. However, there have been few studies in Asian populations. This cross-sectional study aimed to examine whether grip strength is independently associated with dementia after controlling for other related factors in a Korean older population. METHODS: One thousand thirty-eight community-dwelling older people aged 65 or over within a defined geographic area were screened for dementia. Data on grip strength, sit-to-stand score, body mass index (BMI), socio-demographic factors (age, gender, marital status, education), and medical conditions (diabetes, hypertension, heart disease, stroke) were collected. Dementia was diagnosed with the 10/66 dementia diagnostic algorithm. RESULTS: Eleven percent of the participants were found to have dementia. After adjustment for other factors, grip strength (per 8-kg decrease) was independently associated with dementia (odds ratio, 1.59; 95% confidence interval, 1.19-2.14). Adjusted grip strength by BMI interaction terms showed marginal significance (p = 0.098); that is, older people with both reduced grip strength and low BMI were likely to be at higher risk for dementia. CONCLUSIONS: Reduced grip strength was independently associated with dementia in a Korean older population. This association was partially influenced by BMI.
Authors: Ola Sternäng; Chandra A Reynolds; Deborah Finkel; Marie Ernsth-Bravell; Nancy L Pedersen; Anna K Dahl Aslan Journal: Age Ageing Date: 2014-11-01 Impact factor: 10.668
Authors: H L Ong; S H S Chang; E Abdin; J A Vaingankar; A Jeyagurunathan; S Shafie; H Magadi; S A Chong; M Subramaniam Journal: J Nutr Health Aging Date: 2016 Impact factor: 4.075
Authors: Kristen M George; Paola Gilsanz; Rachel L Peterson; Medellena Maria Glymour; Elizabeth Rose Mayeda; Dan M Mungas; Sunita Q Miles; Rachel A Whitmer Journal: Alzheimer Dis Assoc Disord Date: 2021 Jan-Mar 01 Impact factor: 2.357
Authors: Jung Eun Lee; Ki Woong Kim; Nam-Jong Paik; Hak Chul Jang; Chong Bum Chang; Goo Hyun Baek; Young Ho Lee; Hyun Sik Gong Journal: J Bone Metab Date: 2012-11-16