Literature DB >> 21626269

Willingness to vaccinate or get vaccinated with an intradermal seasonal influenza vaccine: a survey of general practitioners and the general public in France and Germany.

Robert Arnou1, Matthias Frank, Thomas Hagel, Alice Prébet.   

Abstract

INTRODUCTION: The elderly are at high risk of severe seasonal influenza and influenza-related death. Annual vaccination can effectively prevent influenza and its complications, and is recommended in the elderly. In the present study, surveys were undertaken in France and Germany to determine whether INTANZA (sanofi pasteur, Val-de-Reuil, France), the first intradermal influenza vaccine, administered using an innovative microneedle injection system, might influence physicians' likelihood of recommending influenza vaccination or the likelihood that the general public would seek influenza vaccination.
METHODS: Physicians (France: n=260; Germany: n=223) and members of the general public aged ≥ 50 years (France: n=1706; Germany: n=1072) completed online surveys. Details of the INTANZA delivery system, and a "product profile" based on the properties of INTANZA, were presented.
RESULTS: Most physicians and the general public found INTANZA and its microneedle injection system appealing. The main benefit of INTANZA, as perceived by physicians and the public, was the small needle size. Physicians also found the high immunogenicity compared with conventional intramuscular (IM) vaccines attractive. The majority of physicians believed that INTANZA would strongly help them to recommend vaccination to their unvaccinated patients (66% to 91%, depending upon patient characteristics); most (61% to 78%) would prefer to prescribe INTANZA rather than an IM vaccine. More than two-thirds of the unvaccinated general public would prefer INTANZA over IM vaccines, and the option of vaccination with INTANZA would encourage a large proportion of them to get vaccinated (60% to 74%), if it was recommended and they were given the choice. Physicians (≥ 82%) agreed that INTANZA may help increase vaccination coverage rates.
CONCLUSION: The results of these surveys indicate that the availability of INTANZA may encourage physicians to recommend influenza vaccination, and members of the general public to get vaccinated. INTANZA may help to improve seasonal influenza vaccination coverage rates.

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Year:  2011        PMID: 21626269     DOI: 10.1007/s12325-011-0035-z

Source DB:  PubMed          Journal:  Adv Ther        ISSN: 0741-238X            Impact factor:   3.845


  15 in total

1.  Immunogenicity and safety of Intanza(®)/IDflu(®) intradermal influenza vaccine in South Korean adults: a multicenter, randomized trial.

Authors:  Sang Hoon Han; Jun Hee Woo; Francoise Weber; Woo Joo Kim; Kyong Ran Peck; Sang Il Kim; Young Hwa Choi; June Myung Kim
Journal:  Hum Vaccin Immunother       Date:  2013-06-18       Impact factor: 3.452

2.  Does Choice of Influenza Vaccine Type Change Disease Burden and Cost-Effectiveness in the United States? An Agent-Based Modeling Study.

Authors:  Jay V DePasse; Kenneth J Smith; Jonathan M Raviotta; Eunha Shim; Mary Patricia Nowalk; Richard K Zimmerman; Shawn T Brown
Journal:  Am J Epidemiol       Date:  2017-05-01       Impact factor: 4.897

Review 3.  Immunogenicity, safety and tolerability of intradermal influenza vaccines.

Authors:  Ivan F N Hung; Kwok-Yung Yuen
Journal:  Hum Vaccin Immunother       Date:  2017-07-06       Impact factor: 3.452

4.  Randomized Controlled Trial to Compare Immunogenicity of Standard-Dose Intramuscular Versus Intradermal Trivalent Inactivated Influenza Vaccine in HIV-Infected Men Who Have Sex With Men in Bangkok, Thailand.

Authors:  Shikha Garg; Prasert Thongcharoen; Prabda Praphasiri; Anupong Chitwarakorn; Pornchai Sathirapanya; Stefan Fernandez; Kamonthip Rungrojcharoenkit; Wannee Chonwattana; Philip A Mock; Wichuda Sukwicha; Jacqueline M Katz; Marc-Alain Widdowson; Marcel E Curlin; Robert V Gibbons; Timothy H Holtz; Fatimah S Dawood; Sonja J Olsen
Journal:  Clin Infect Dis       Date:  2015-10-20       Impact factor: 9.079

5.  The immunogenicity of the intradermal injection of seasonal trivalent influenza vaccine containing influenza A(H1N1)pdm09 in COPD patients soon after a pandemic.

Authors:  Benjamas Chuaychoo; Uraiwan Kositanont; Nuttapol Rittayamai; Parichat Niyomthong; Thaweesak Songserm; Khun Nanta Maranetra; Kanokwan Rattanasaengloet; Arth Nana
Journal:  Hum Vaccin Immunother       Date:  2016-05-06       Impact factor: 3.452

Review 6.  Fluzone® intra-dermal (Intanza®/Istivac® Intra-dermal): An updated overview.

Authors:  Nicola Luigi Bragazzi; Andrea Orsi; Filippo Ansaldi; Roberto Gasparini; Giancarlo Icardi
Journal:  Hum Vaccin Immunother       Date:  2016-05-31       Impact factor: 3.452

7.  Head-to-head comparison of an intradermal and a virosome influenza vaccine in patients over the age of 60: evaluation of immunogenicity, cross-protection, safety and tolerability.

Authors:  Filippo Ansaldi; Andrea Orsi; Daniela de Florentiis; Valentina Parodi; Emanuela Rappazzo; Martina Coppelli; Paolo Durando; Giancarlo Icardi
Journal:  Hum Vaccin Immunother       Date:  2013-01-07       Impact factor: 3.452

8.  Does cost-effectiveness of influenza vaccine choice vary across the U.S.? An agent-based modeling study.

Authors:  Jay V DePasse; Mary Patricia Nowalk; Kenneth J Smith; Jonathan M Raviotta; Eunha Shim; Richard K Zimmerman; Shawn T Brown
Journal:  Vaccine       Date:  2017-06-09       Impact factor: 3.641

9.  Potential Consequences of Not Using Live Attenuated Influenza Vaccine.

Authors:  Kenneth J Smith; Mary Patricia Nowalk; Angela Wateska; Shawn T Brown; Jay V DePasse; Jonathan M Raviotta; Eunha Shim; Richard K Zimmerman
Journal:  Am J Prev Med       Date:  2017-04-18       Impact factor: 5.043

Review 10.  Intanza (®) 9 µg intradermal seasonal influenza vaccine for adults 18 to 59 years of age.

Authors:  Isabel Leroux-Roels; Françoise Weber
Journal:  Hum Vaccin Immunother       Date:  2013-01       Impact factor: 3.452

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