Literature DB >> 21626005

Diagnostic and management of pediatric brain stem abscess, a case-based update.

Houssine Ghannane1, Mehdi Laghmari, Khalid Aniba, Mohammed Lmejjati, Saïd Ait Benali.   

Abstract

PURPOSE: Authors report their experience of a pediatric brain stem abscess with a literature review.
METHODS: A 2.5-year-old girl first displayed bacterial otitis 3 months before admission. Diagnosis of brain stem abscess was delayed, despite plethoric neurological signs. She complained of right hemiparesis, headache, squint, dysphagia, and false way inhalation pneumopathy. Brain magnetic resonance imaging revealed presence of an abscess in the pons, prompting for a microsurgical pus aspiration. Postoperative course was regular with a total neurological recovery. Clinical and radiological screening showed progressive regression of the pontine lesion after 4 months, despite persistence of a mild contrast enhancement. Present case is the 18th pediatric brain stem abscess reported in literature.
RESULTS: Mean age of occurrence is 8.1 ± 4 years (range 0.75-16) without gender predominance. High morbidity is typical and essentially involves motor functions. The most common clinical signs are raised intracranial pressure, motor limbs deficit, and cranial nerve palsies. Fever was found in 10 out of 18 cases (56%). Three patients received conservative medical treatment. Three patients underwent stereotactic aspiration and 12 others underwent microsurgical aspiration or excision. No mortality was reported since the eighties. However, morbidity is still high.
CONCLUSION: High clinical index of suspicion is necessary to improve functional outcome. Stereotactic-guided or microsurgical aspiration are still good therapeutic options. The rarity of pediatric brain stem abscesses and the need of optimal management make this case-based update very peculiar.

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Year:  2011        PMID: 21626005     DOI: 10.1007/s00381-011-1441-x

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  56 in total

1.  Brainstem abscess complicating tetralogy of Fallot successfully treated with antibiotics alone.

Authors:  J D Pandian; N V Moosa; P J Cherian; K Radhakrishnan
Journal:  Neurol India       Date:  2000-09       Impact factor: 2.117

2.  Brain abscess in 142 patients: factors influencing outcome and mortality.

Authors:  Jen-Ho Tseng; Ming-Yuan Tseng
Journal:  Surg Neurol       Date:  2006-06

Review 3.  Management of brain abscess: an overview.

Authors:  Ranjith K Moorthy; Vedantam Rajshekhar
Journal:  Neurosurg Focus       Date:  2008       Impact factor: 4.047

Review 4.  Infections of the central nervous system.

Authors:  G C Townsend; W M Scheld
Journal:  Adv Intern Med       Date:  1998

5.  Production of experimental brain abscess in the rat.

Authors:  H R Winn; M Mendes; P Moore; C Wheeler; G Rodeheaver
Journal:  J Neurosurg       Date:  1979-11       Impact factor: 5.115

6.  Bilateral mycotic cerebral abscess due to aspergillosis--a case report.

Authors:  Kanakalata Dash; Asaranti Dash; Sujata Pujari; Bidyutprava Das; Kumudini Devi; Raghumani Mohanty
Journal:  Indian J Pathol Microbiol       Date:  2006-10       Impact factor: 0.740

7.  Improved management of multiple brain abscesses: a combined surgical and medical approach.

Authors:  A N Mamelak; T J Mampalam; W G Obana; M L Rosenblum
Journal:  Neurosurgery       Date:  1995-01       Impact factor: 4.654

8.  Brain stem abscesses in childhood.

Authors:  T Suzer; E Coskun; B Cirak; B Yagci; K Tahta
Journal:  Childs Nerv Syst       Date:  2004-09-02       Impact factor: 1.475

Review 9.  Multiple cerebral abscesses because of Listeria monocytogenes: three case reports and a literature review of supratentorial listerial brain abscess(es).

Authors:  Lawrence A Cone; Millie M Leung; Richard G Byrd; Gary M Annunziata; Richard Y Lam; Brian K Herman
Journal:  Surg Neurol       Date:  2003-04

Review 10.  Management of brain abscesses in children.

Authors:  James L Frazier; Edward S Ahn; George I Jallo
Journal:  Neurosurg Focus       Date:  2008       Impact factor: 4.047

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  3 in total

1.  Freiburg neuropathology case conference : Brainstem tumor in a child.

Authors:  C A Taschner; O Staszewski; P Reinacher; H Urbach; C P Simon-Gabriel; M Prinz
Journal:  Clin Neuroradiol       Date:  2016-09       Impact factor: 3.649

2.  Brainstem abscess treated conservatively.

Authors:  Camila Furtado Leao; Maira Piani Couto; Jose Antonio Santos de Lima; Eric Homero Albuquerque Paschoal; Jose Reginaldo Nascimento Brito
Journal:  Surg Neurol Int       Date:  2020-07-25

Review 3.  Clinical features, microbiology, and management of pediatric brainstem abscess.

Authors:  Łukasz Antkowiak; Monika Putz; Marek Mandera
Journal:  Childs Nerv Syst       Date:  2020-07-30       Impact factor: 1.475

  3 in total

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