Literature DB >> 2162583

[Mechanisms of the development of immunodependent inflammation in silicosis].

T I Grishina, O G Alekseeva, N L Aĭzina, A P Volkova, R G Girdo, Iu A Loshchilov, V V Sokolov.   

Abstract

Patients with uncomplicated silicosis were found to develop chronic immunodependent inflammation caused by an adjuvant effect of silica and characterized by autoimmune, histamine- and complement-dependent components. Reduced specific and non-specific antimicrobial defence underlies frequent complication of silicosis by tuberculosis and nonspecific infectious diseases of the bronchopulmonary system. A diagram showing the development of immunodependent inflammation in silicosis is presented.

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Year:  1990        PMID: 2162583

Source DB:  PubMed          Journal:  Vestn Akad Med Nauk SSSR        ISSN: 0002-3027


  1 in total

1.  Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study.

Authors:  Shaofan Weng; Lihua Wang; Yi Rong; Yuewei Liu; Xin Wang; Hongyu Guan; Weihong Chen
Journal:  PLoS One       Date:  2015-10-23       Impact factor: 3.240

  1 in total

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