Literature DB >> 21625325

Psychiatric molecular genetics and the ethics of social promises.

John Z Sadler1, Daniel W Foster.   

Abstract

A recent literature review of commentaries and 'state of the art' articles from researchers in psychiatric genetics (PMG) offers a consensus about progress in the science of genetics, disappointments in the discovery of new and effective treatments, and a general optimism about the future of the field. I argue that optimism for the field of psychiatric molecular genetics (PMG) is overwrought, and consider progress in the field in reference to a sample estimate of US National Institute of Mental Health funding for this paradigm for the years 2008 and 2009. I conclude that the amounts of financial investment in PMG is questionable from an ethical perspective, given other research and clinical needs in the USA.

Entities:  

Year:  2011        PMID: 21625325      PMCID: PMC3102532          DOI: 10.1007/s11673-010-9273-z

Source DB:  PubMed          Journal:  J Bioeth Inq        ISSN: 1176-7529            Impact factor:   1.352


  34 in total

1.  Psychiatric genetics: what to expect.

Authors:  Joachim F Hallmayer
Journal:  Curr Psychiatry Rep       Date:  2004-06       Impact factor: 5.285

2.  [Review of: Healy, David. The Creation of psychopharmacology. Cambridge, MA: Harvard University Press, 2002].

Authors:  Nathan Greenslit
Journal:  Hist Psychiatry       Date:  2004-06

3.  Multiple personal genomes await.

Authors:  J Craig Venter
Journal:  Nature       Date:  2010-04-01       Impact factor: 49.962

4.  Genomic analysis of mental illness: a changing landscape.

Authors:  Jon McClellan; Mary-Claire King
Journal:  JAMA       Date:  2010-06-23       Impact factor: 56.272

5.  Psychiatric genetics: The brains of the family.

Authors:  Alison Abbott
Journal:  Nature       Date:  2008-07-10       Impact factor: 49.962

Review 6.  Modeling madness in mice: one piece at a time.

Authors:  P Alexander Arguello; Joseph A Gogos
Journal:  Neuron       Date:  2006-10-05       Impact factor: 17.173

Review 7.  The nature of genetic influences on behavior: lessons from "simpler" organisms.

Authors:  Kenneth S Kendler; Ralph J Greenspan
Journal:  Am J Psychiatry       Date:  2006-10       Impact factor: 18.112

Review 8.  Update on psychiatric genetics.

Authors:  Stephan Züchner; Sushma T Roberts; Marcy C Speer; Jean C Beckham
Journal:  Genet Med       Date:  2007-06       Impact factor: 8.822

Review 9.  Strategy for investigating interactions between measured genes and measured environments.

Authors:  Terrie E Moffitt; Avshalom Caspi; Michael Rutter
Journal:  Arch Gen Psychiatry       Date:  2005-05

10.  Grand challenges and opportunities for molecular psychiatry research: a perspective.

Authors:  Ming D Li
Journal:  Front Psychiatry       Date:  2010-01-18       Impact factor: 4.157

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  1 in total

1.  Two kinds of autism: a comparison of distinct understandings of psychiatric disease.

Authors:  Berend Verhoeff
Journal:  Med Health Care Philos       Date:  2016-03
  1 in total

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