Literature DB >> 21623593

Precision, morphology, and histology of corneal flap cuts using a 200-kHz femtosecond laser.

Ramin Khoramnia1, Josefina P Salgado, Chris P Lohmann, Karin A Kobuch, Christoph Winkler von Mohrenfels.   

Abstract

PURPOSE: Laser-assisted in situ keratomileusis (LASIK) requires precise corneal flap cutting. Especially the creation of thin flaps has recently gained importance for thin-flap LASIK. Currently, there is a trend towards faster femtosecond lasers that can produce flaps in a short period of time. We analyzed flaps created with a 200-kHz femtosecond laser concerning their cut precision, morphology, and histology.
METHODS: Femtosecond laser flap cutting was performed on 36 porcine cadaver eyes using the prototype 200-kHz femtosecond laser UltraFlap (WaveLight GmbH, Erlangen, Germany). The eyes were assigned to 3 thickness groups, with a cut depth of 100 µm, 130 µm, or 180 µm, respectively. Additionally, flap diameters were varied, ranging from 8.0 mm to 9.5 mm. Flap thicknesses were determined with a micrometer gauge. Flap diameters were measured with a sliding caliper. Furthermore, flaps were created for histologic examination.
RESULTS: There were no complications during flap creation. The mean flap thickness and standard deviation was (in micrometers) 96.33 ± 7.45 (intended thickness: 100), 134.67 ± 4.96 (intended thickness: 130), and 174.59 ± 9.35 (intended thickness: 180), respectively. The flap diameter revealed a mean (in mm) of 8.03 ± 0.15 (intended diameter: 8.0), 8.56 ± 0.10 (intended diameter: 8.5), 9.09 ± 0.10 (intended diameter: 9.0), and 9.54 ± 0.15 (intended diameter: 9.5), respectively. Histologic examination showed very little to almost no changes in the structure of the corneal stroma.
CONCLUSIONS: Flap creation could be performed easily without any complications. The morphology and accuracy of the cuts were very reliable and precise. Histology showed a smooth cut.

Entities:  

Mesh:

Year:  2012        PMID: 21623593     DOI: 10.5301/EJO.2011.8376

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  4 in total

1.  FS200 femtosecond laser LASIK flap digital analysis parameter evaluation: comparing two different types of patient interface applanation cones.

Authors:  A John Kanellopoulos; George Asimellis
Journal:  Clin Ophthalmol       Date:  2013-06-10

2.  Effects of flap diameter on dry eye parameters and corneal sensation after femtosecond laser-assisted LASIK.

Authors:  Yuan-Che Tai; Chi-Chin Sun
Journal:  Taiwan J Ophthalmol       Date:  2019-09-12

3.  Three-dimensional LASIK flap thickness variability: topographic central, paracentral and peripheral assessment, in flaps created by a mechanical microkeratome (M2) and two different femtosecond lasers (FS60 and FS200).

Authors:  A John Kanellopoulos; George Asimellis
Journal:  Clin Ophthalmol       Date:  2013-04-03

4.  Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique.

Authors:  A John Kanellopoulos; George Asimellis
Journal:  Clin Ophthalmol       Date:  2013-02-15
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.