Literature DB >> 2162132

Multicenter clinical evaluation of the Du Pont Herpchek HSV ELISA, a new rapid diagnostic test for the direct detection of herpes simplex virus.

D A Baker1, D Pavan-Langston, B Gonik, P O Milch, E C Dunkel, A Berkowitz, M B Woodin, A Philip, R J Vander-Mallie, M N Bobrow.   

Abstract

A new 4h rapid enzyme-immunoassay for direct detection of herpes simplex virus (HSV) antigen (Du Pont Herpchek) was evaluated with 743 clinical samples collected at obstetrics and gynecology (OB/GYN), sexually transmitted diseases (STD), and ophthalmology clinics. The sensitivity and specificity of Herpchek was 98.0% and 98.4% respectively compared to virus isolation in cell culture. Confirmatory blocking ELISA tests, clinical history and follow up indicate that the true specificity of the test is 100%.

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Year:  1990        PMID: 2162132     DOI: 10.1007/978-1-4613-0601-6_6

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  3 in total

1.  Genital herpes.

Authors:  A M Geretti
Journal:  Sex Transm Infect       Date:  2006-12       Impact factor: 3.519

2.  Comparison of a direct antigen enzyme immunoassay, Herpchek, with cell culture for detection of herpes simplex virus from clinical specimens.

Authors:  L Verano; F J Michalski
Journal:  J Clin Microbiol       Date:  1995-05       Impact factor: 5.948

3.  Herpes simplex virus detection from genital lesions: a comparative study using antigen detection (HerpChek) and culture.

Authors:  R W Cone; P D Swenson; A C Hobson; M Remington; L Corey
Journal:  J Clin Microbiol       Date:  1993-07       Impact factor: 5.948

  3 in total

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