Literature DB >> 21620842

The cell biology of the unfolded protein response.

J Alan Diehl1, Serge Y Fuchs, Costantinos Koumenis.   

Abstract

The unfolded protein response (UPR) is an ensemble of signal transduction pathways that respond to perturbations in the oxidative, pro-folding environment of the endoplasmic reticulum. During the past decade, ongoing research implicated these pathways in maintaining homeostasis of cells and organisms exposed to various stresses. Herein, we highlight recent findings regarding the functional role of the UPR in both normal and pathophysiologic processes.
Copyright © 2011 AGA Institute. Published by Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21620842      PMCID： PMC3129462          DOI： 10.1053/j.gastro.2011.05.018

Source DB:  PubMed          Journal:  Gastroenterology        ISSN： 0016-5085            Impact factor:   22.682


  74 in total

Review 1.  The unfolded protein response in nutrient sensing and differentiation.

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Journal:  Nat Rev Mol Cell Biol       Date:  2002-06       Impact factor: 94.444

2.  Ligand-independent pathway that controls stability of interferon alpha receptor.

Authors:  Jianghuai Liu; Alexander Plotnikov; Anamika Banerjee; K G Suresh Kumar; Josiane Ragimbeau; Zrinka Marijanovic; Darren P Baker; Sandra Pellegrini; Serge Y Fuchs
Journal:  Biochem Biophys Res Commun       Date:  2007-12-31       Impact factor: 3.575

Review 3.  The unfolded protein response and autophagy: herpesviruses rule!

Authors:  Dong Yun Lee; Jisook Lee; Bill Sugden
Journal:  J Virol       Date:  2008-09-10       Impact factor: 5.103

4.  Regulation of hepatic lipogenesis by the transcription factor XBP1.

Authors:  Ann-Hwee Lee; Erez F Scapa; David E Cohen; Laurie H Glimcher
Journal:  Science       Date:  2008-06-13       Impact factor: 47.728

Review 5.  Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3.

Authors:  Gulam Waris; Keith D Tardif; Aleem Siddiqui
Journal:  Biochem Pharmacol       Date:  2002-11-15       Impact factor: 5.858

6.  PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.

Authors:  Ekaterina Bobrovnikova-Marjon; Georgia Hatzivassiliou; Christina Grigoriadou; Margarita Romero; Douglas R Cavener; Craig B Thompson; J Alan Diehl
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-13       Impact factor: 11.205

7.  Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif.

Authors:  K G Suresh Kumar; Bentley Varghese; Anamika Banerjee; Darren P Baker; Stefan N Constantinescu; Sandra Pellegrini; Serge Y Fuchs
Journal:  J Biol Chem       Date:  2008-05-12       Impact factor: 5.157

8.  XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.

Authors:  Arthur Kaser; Ann-Hwee Lee; Andre Franke; Jonathan N Glickman; Sebastian Zeissig; Herbert Tilg; Edward E S Nieuwenhuis; Darren E Higgins; Stefan Schreiber; Laurie H Glimcher; Richard S Blumberg
Journal:  Cell       Date:  2008-09-05       Impact factor: 41.582

9.  Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor.

Authors:  Jianghuai Liu; Wei-Chun HuangFu; K G Suresh Kumar; Juan Qian; James P Casey; Robert B Hamanaka; Christina Grigoriadou; Rafael Aldabe; J Alan Diehl; Serge Y Fuchs
Journal:  Cell Host Microbe       Date:  2009-01-22       Impact factor: 21.023

10.  Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.

Authors:  Wei-Xing Zong; Chi Li; Georgia Hatzivassiliou; Tullia Lindsten; Qian-Chun Yu; Junying Yuan; Craig B Thompson
Journal:  J Cell Biol       Date:  2003-07-07       Impact factor: 10.539
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  46 in total

Review 1.  Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation.

Authors:  Sujatha Muralidharan; Pranoti Mandrekar
Journal:  J Leukoc Biol       Date:  2013-08-29       Impact factor: 4.962

Review 2.  SERPINB3 and B4: From biochemistry to biology.

Authors:  Yu Sun; Namratha Sheshadri; Wei-Xing Zong
Journal:  Semin Cell Dev Biol       Date:  2016-09-13       Impact factor: 7.727

3.  miRNA-211 stops the clock.

Authors:  Carmit Levy; Tamar Golan; David E Fisher
Journal:  Noncoding RNA Investig       Date:  2018-05-06

4.  Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.

Authors:  Anthony C Brandt; Lisa McNally; Ellen L Lorimer; Bethany Unger; Olivia J Koehn; Kiall F Suazo; Lisa Rein; Aniko Szabo; Shirng-Wern Tsaih; Mark D Distefano; Michael J Flister; Frank Rigo; Mark T McNally; Carol L Williams
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-04       Impact factor: 11.205

Review 5.  The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies.

Authors:  B Luo; A S Lee
Journal:  Oncogene       Date:  2012-04-16       Impact factor: 9.867

6.  Type I interferons mediate pancreatic toxicities of PERK inhibition.

Authors:  Qiujing Yu; Bin Zhao; Jun Gui; Kanstantsin V Katlinski; Angela Brice; Yan Gao; ChangHong Li; Jake A Kushner; Constantinos Koumenis; J Alan Diehl; Serge Y Fuchs
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-01       Impact factor: 11.205

Review 7.  Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease.

Authors:  Xue-Qun Zhang; Cheng-Fu Xu; Chao-Hui Yu; Wei-Xing Chen; You-Ming Li
Journal:  World J Gastroenterol       Date:  2014-02-21       Impact factor: 5.742

Review 8.  Oncolytic virotherapy and immunogenic cancer cell death: sharpening the sword for improved cancer treatment strategies.

Authors:  Samuel T Workenhe; Karen L Mossman
Journal:  Mol Ther       Date:  2013-10-19       Impact factor: 11.454

9.  PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.

Authors:  Yan Gao; Daniel J Sartori; Changhong Li; Qian-Chun Yu; Jake A Kushner; M Celeste Simon; J Alan Diehl
Journal:  Mol Cell Biol       Date:  2012-10-15       Impact factor: 4.272

10.  Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses.

Authors:  S Bhattacharya; W-C HuangFu; G Dong; J Qian; D P Baker; J Karar; C Koumenis; J A Diehl; S Y Fuchs
Journal:  Oncogene       Date:  2012-10-08       Impact factor: 9.867
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