Literature DB >> 21620486

Differential conditioned fear response predicts duloxetine treatment outcome in male veterans with PTSD: a pilot study.

Deane E Aikins1, Eric D Jackson, Alicia Christensen, Espen Walderhaug, Sonia Afroz, Alexander Neumeister.   

Abstract

This pilot study tested whether posttraumatic stress disorder (PTSD) patients with impaired conditioned fear acquisition were refractory to open-label duloxetine treatment. Patients with a differential conditioned fear response at pre-treatment subsequently demonstrated significant reductions in PTSD symptoms. These data provide initial evidence of a putative biomarker of selective treatment response in PTSD. 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21620486     DOI： 10.1016/j.psychres.2011.05.009

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  8 in total

1.  Pharmacologic Therapy for Posttraumatic Stress Disorder: Review of Prescriptions and Potential Drug-Drug Interactions in a Military Cohort.

Authors:  Kara L Jablonski; Maria D Devore; Margaret A Ryan; Emily L Streeter; Jerlyn C Tolentino; Angelica A Klinski; Nahed Bahlawan
Journal:  Prim Care Companion CNS Disord       Date:  2015-12-03

Review 2.  Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder.

Authors:  N W Gilpin; J L Weiner
Journal:  Genes Brain Behav       Date:  2016-11-18       Impact factor: 3.449

Review 3.  The role of stress and fear in the development of mental disorders.

Authors:  Polaris Gonzalez; Karen G Martinez
Journal:  Psychiatr Clin North Am       Date:  2014-10-11

4.  Characterization of electroencephalographic and biochemical responses at 5-HT promoting drug-induced onset of serotonin syndrome in rats.

Authors:  Zhiyuan Ma; Mary Rudacille; Howard M Prentice; Rui Tao
Journal:  J Neurochem       Date:  2013-01-28       Impact factor: 5.372

5.  Single prolonged stress impairs social and object novelty recognition in rats.

Authors:  Andrew L Eagle; Chris J Fitzpatrick; Shane A Perrine
Journal:  Behav Brain Res       Date:  2013-09-12       Impact factor: 3.332

6.  Updating versus Exposure to Prevent Consolidation of Conditioned Fear.

Authors:  Victoria Pile; Thorsten Barnhofer; Jennifer Wild
Journal:  PLoS One       Date:  2015-04-22       Impact factor: 3.240

Review 7.  Biomarkers in posttraumatic stress disorder: overview and implications for future research.

Authors:  Ulrike Schmidt; Sebastian F Kaltwasser; Carsten T Wotjak
Journal:  Dis Markers       Date:  2013-07-21       Impact factor: 3.434

Review 8.  Single-Prolonged Stress: A Review of Two Decades of Progress in a Rodent Model of Post-traumatic Stress Disorder.

Authors:  Michael J Lisieski; Andrew L Eagle; Alana C Conti; Israel Liberzon; Shane A Perrine
Journal:  Front Psychiatry       Date:  2018-05-15       Impact factor: 4.157
  8 in total

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