Nirupama Anne1, Ratnakishore Pallapothu. 1. Department of Surgery, Our Lady of Lourdes Memorial Hospital, Binghamton, NY, USA. nirupamaanne@yahoo.com
Abstract
BACKGROUND: Unusual metastatic presentation of intra-ocular melanoma. STUDY DESIGN: Case report. DISCUSSION: Extra-regional lymphatic spread of intra-ocular melanoma has not been reported previously in the literature. The usual pattern of metastasis for intra-ocular melanoma is hematogenous. There are few reports of regional spread to the maxillofacial bones. We report an interesting case of a 51 year old female with prior history of right eye melanoma, now presenting with metastasis to the left axilla, which is an extra-regional nodal basin. CONCLUSION: In female patients presenting with an isolated axillary mass, with a negative breast work up and known prior history of melanoma, the differential diagnosis should include possible metastatic melanoma. Core biopsy will confirm the diagnosis and tailor subsequent management.
BACKGROUND: Unusual metastatic presentation of intra-ocular melanoma. STUDY DESIGN: Case report. DISCUSSION: Extra-regional lymphatic spread of intra-ocular melanoma has not been reported previously in the literature. The usual pattern of metastasis for intra-ocular melanoma is hematogenous. There are few reports of regional spread to the maxillofacial bones. We report an interesting case of a 51 year old female with prior history of right eye melanoma, now presenting with metastasis to the left axilla, which is an extra-regional nodal basin. CONCLUSION: In female patients presenting with an isolated axillary mass, with a negative breast work up and known prior history of melanoma, the differential diagnosis should include possible metastatic melanoma. Core biopsy will confirm the diagnosis and tailor subsequent management.
Authors: Claire M Vajdic; Anne Kricker; Michael Giblin; John McKenzie; Joanne Aitken; Graham G Giles; Bruce K Armstrong Journal: Int J Cancer Date: 2002-09-10 Impact factor: 7.396
Authors: Ludwig M Heindl; Tanja N Hofmann; Harald L J Knorr; Carmen Rummelt; Falk Schrödl; Ursula Schlötzer-Schrehardt; Leonard M Holbach; Gottfried O H Naumann; Friedrich E Kruse; Claus Cursiefen Journal: Invest Ophthalmol Vis Sci Date: 2009-01-17 Impact factor: 4.799