Literature DB >> 21619455

Economic burden of resected squamous cell carcinoma of the head and neck in a US managed-care population.

Mayur M Amonkar1, Benjamin Chastek, Navendu Samant, April Teitelbaum.   

Abstract

BACKGROUND: Squamous cell carcinoma of the head and neck (SCCHN) places a high burden on society and poses complex challenges to healthcare providers.
METHODS: Retrospective claims-based analysis of commercially insured patients identified between 01-31-04 and 12-31-07 with diagnostic evidence of cancer of the lip, tongue, oral cavity, pharynx, or larynx who underwent surgical resection during identification period. Outcomes included treatment patterns, healthcare utilization, and costs. All study variables were analyzed descriptively.
RESULTS: Among the 1104 patients in the final study sample, 71.9% were male, with mean age 56.6 years. On average, patients were followed for 830 days (range of mean days: 805 for lip or tongue cancer to 847 for pharyngeal cancer). About half received radiation therapy during follow-up, whereas only 16.2% received chemotherapy. Patients with pharyngeal cancer were most likely to undergo chemotherapy. After their index surgery, 57.9% of patients had ≥1 inpatient stay, 44.9% had ≥1 ER visit, and all had ≥1 ambulatory visit. The percentage with ≥1 inpatient stay post-index was highest among patients with pharyngeal cancer (73.0%) and lowest in the laryngeal cancer cohort (49.5%). Mean number of hospitalized days, ER visits, and ambulatory visits was 0.45, 0.69, and 27.4, respectively, per-patient per-year. Overall, patients incurred ~$94 million in cost following index surgery ($85,000 per-person, on average). Mean total healthcare cost was $34,450 per-patient per-year, the bulk of which comprised medical expenses ($32,401). The highest mean healthcare cost was incurred by the pharyngeal cancer cohort ($40,214).
CONCLUSIONS: Patients with resected SCCHN incur substantial healthcare costs and have high utilization rates. Results of this analysis are primarily applicable to resected SCCHN in a managed-care setting, and therefore may not be generalizable to the entire US population. Furthermore, disease stage is an important factor impacting outcomes, but these analyses did not stratify patients according to disease stage.

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Year:  2011        PMID: 21619455     DOI: 10.3111/13696998.2011.584096

Source DB:  PubMed          Journal:  J Med Econ        ISSN: 1369-6998            Impact factor:   2.448


  7 in total

1.  Economic Analysis of a Three-Arm RCT Exploring the Delivery of Intensive, Prophylactic Swallowing Therapy to Patients with Head and Neck Cancer During (Chemo)Radiotherapy.

Authors:  Laurelie R Wall; Sanjeewa Kularatna; Elizabeth C Ward; Bena Cartmill; Anne J Hill; Elizabeth Isenring; Joshua Byrnes; Sandro V Porceddu
Journal:  Dysphagia       Date:  2018-12-04       Impact factor: 3.438

2.  Health care costs and resource utilization, including patient burden, associated with novel-agent-based treatment versus other therapies for multiple myeloma: findings using real-world claims data.

Authors:  April Teitelbaum; Abbie Ba-Mancini; Hui Huang; Henry J Henk
Journal:  Oncologist       Date:  2013-01-08

3.  Mutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma.

Authors:  Sean M McBride; S Michael Rothenberg; William C Faquin; Annie W Chan; John R Clark; Leif W Ellisen; Lori J Wirth
Journal:  Head Neck       Date:  2014-03-10       Impact factor: 3.147

4.  Analysis of Charges Associated with Definitive Nonsurgical Therapy for Early-Stage Lateralized Tonsil Cancer.

Authors:  Carol M Lewis; Gregory M Chronowski; Wenli Dong; G Brandon Gunn; David I Rosenthal; Randal S Weber
Journal:  Ann Surg Oncol       Date:  2014-12-18       Impact factor: 5.344

5.  Determinants of End-of-Life Expenditures in Patients with Oral Cancer in Taiwan: A Population-Based Study.

Authors:  Ching-Chih Lee; Ting-Shou Chang; Cheng-Jung Wu; Ching-Chieh Yang; Po-Chun Chen
Journal:  PLoS One       Date:  2015-05-06       Impact factor: 3.240

6.  Cost-effectiveness analysis of a postoperative clinical care pathway in head and neck surgery with microvascular reconstruction.

Authors:  Jonathan F Dautremont; Luke R Rudmik; Justin Yeung; Tiffany Asante; Steve C Nakoneshny; Monica Hoy; Amanda Lui; Shamir P Chandarana; Thomas W Matthews; Christiaan Schrag; Joseph C Dort
Journal:  J Otolaryngol Head Neck Surg       Date:  2013-12-19

Review 7.  The economic burden of head and neck cancer: a systematic literature review.

Authors:  Erika Wissinger; Ingolf Griebsch; Juliane Lungershausen; Talia Foster; Chris L Pashos
Journal:  Pharmacoeconomics       Date:  2014-09       Impact factor: 4.981

  7 in total

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