Literature DB >> 21618710

Adult granulosa cell tumor presenting as metastases to the pleural and peritoneal cavity.

Nalini Gupta1, Arvind Rajwanshi, Pranab Dey, Vanita Suri.   

Abstract

Ovarian tumors of sex-cord stromal derivation rarely exfoliate malignant cells in serous effusions. Adult granulosa cell tumor (AGCT) often presents as a stage I disease and association with ascites is about 10%. AGCT is rarely known to exfoliate tumor cells in the ascitic fluid. Exfoliation of malignant cells in the pleural fluid is rarer and has not been described previously in literature to the best of our knowledge. We report a case of AGCT presenting as stage IV disease with exfoliation of malignant cells in the pleural and ascitic fluid with exudative effusions. We wish to emphasize on cytomorphologic features of AGCT to differentiate the same from malignant epithelial tumors. A precise diagnosis in such a case may be possible on serous body fluid cytology with a combined clinical and cytopathologic approach.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 21618710     DOI: 10.1002/dc.21675

Source DB:  PubMed          Journal:  Diagn Cytopathol        ISSN: 1097-0339            Impact factor:   1.582


  3 in total

1.  Adult granulosa cell tumor presenting with massive ascites, elevated CA-125 level, and low (18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography.

Authors:  Ji Young Tak; Gun Oh Chong; Ji Y Park; Seung Jeong Lee; Yoon Hee Lee; Dae Gy Hong
Journal:  Obstet Gynecol Sci       Date:  2015-09-22

2.  Cytologic features of sex cord-stromal tumors in women.

Authors:  Liz N Edmund; Abeer M Salama; Rajmohan Murali
Journal:  Cancer Cytopathol       Date:  2021-08-19       Impact factor: 4.264

3.  Peritoneal washing cytology in an adult granulosa cell tumor: A case report and review of literature.

Authors:  Alev O Atilgan; Merih Tepeoglu; Ozlem Ozen; Banu Bilezikçi
Journal:  J Cytol       Date:  2013-01       Impact factor: 1.000

  3 in total

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