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Literature DB >> 21617971

Research progress on Livin protein: an inhibitor of apoptosis.

Abstract

Livin is a member of the inhibitors of apoptosis (IAP) family, which plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Abnormal Livin expression is sometimes detected during the process of cancer formation and/or progression. Thus, Livin research may provide an opportunity for the development of potential therapy for Livin-relevant cancers. In this review, we introduce Livin structure, biological function, and its role in cancer formation and progression and the possible interventions for cancer therapy.

Entities: Disease Gene

Mesh：

Substances：

Year: 2011 PMID： 21617971 DOI： 10.1007/s11010-011-0873-7

Source DB: PubMed Journal: Mol Cell Biochem ISSN： 0300-8177 Impact factor: 3.396

67 in total

1. Detection of anti-livin antibody in gastrointestinal cancer patients.

Authors: Atsuhito Yagihashi; Koichi Asanuma; Naoki Tsuji; Toshihiko Torigoe; Noriyuki Sato; Koichi Hirata; Naoki Watanabe
Journal: Clin Chem Date: 2003-07 Impact factor: 8.327

Review 2. Strategies for silencing human disease using RNA interference.

Authors: Daniel H Kim; John J Rossi
Journal: Nat Rev Genet Date: 2007-03 Impact factor: 53.242

3. SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP).

Authors: Domagoj Vucic; Kurt Deshayes; Heidi Ackerly; Maria Teresa Pisabarro; Saloumeh Kadkhodayan; Wayne J Fairbrother; Vishva M Dixit
Journal: J Biol Chem Date: 2002-01-18 Impact factor: 5.157

4. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction.

Authors: Jan C Schmollinger; Robert H Vonderheide; Kara M Hoar; Britta Maecker; Joachim L Schultze; F Stephen Hodi; Robert J Soiffer; Ken Jung; Marcelo J Kuroda; Norman L Letvin; Edward A Greenfield; Martin Mihm; Jeffery L Kutok; Glenn Dranoff
Journal: Proc Natl Acad Sci U S A Date: 2003-03-07 Impact factor: 11.205

5. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.

Authors: N Roy; Q L Deveraux; R Takahashi; G S Salvesen; J C Reed
Journal: EMBO J Date: 1997-12-01 Impact factor: 11.598

6. Detection of autoantibodies to livin and survivin in Sera from lung cancer patients.

Authors: Atsuhito Yagihashi; Koichi Asanuma; Daisuke Kobayashi; Naoki Tsuji; Yasuharu Shijubo; Shosaku Abe; Yoshihiko Hirohashi; Toshihiko Torigoe; Noriyuki Sato; Naoki Watanabe
Journal: Lung Cancer Date: 2005-01-08 Impact factor: 5.705

7. Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy.

Authors: Rita Bayer Lopes; Rathi Gangeswaran; Iain A McNeish; Yaohe Wang; Nick R Lemoine
Journal: Int J Cancer Date: 2007-06-01 Impact factor: 7.396

Review 8. Targeting melanoma inhibitor of apoptosis protein with cancer immunotherapy.

Authors: J C Schmollinger; G Dranoff
Journal: Apoptosis Date: 2004-05 Impact factor: 4.677

9. Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer.

Authors: Shui Ping Tu; Xiao Hua Jiang; Marie C M Lin; Jian Tao Cui; Yi Yang; Ching Tung Lum; Bing Zou; Yan Bo Zhu; Shi Hu Jiang; Wai Man Wong; Annie On-On Chan; Man Fung Yuen; Shiu Kum Lam; Hsiang Fu Kung; Benjamin Chun-Yu Wong
Journal: Cancer Res Date: 2003-11-15 Impact factor: 12.701

10. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene.

Authors: Irena Crnkovic-Mertens; Felix Hoppe-Seyler; Karin Butz
Journal: Oncogene Date: 2003-11-13 Impact factor: 9.867

17 in total

1. HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line.

Authors: Arin N Graner; Justin E Hellwinkel; Alex M Lencioni; Helen J Madsen; Tessa A Harland; Paul Marchando; Ger J Nguyen; Mary Wang; Laura M Russell; Lynne T Bemis; Thomas J Anchordoquy; Michael W Graner
Journal: Int J Hyperthermia Date: 2016-12-20 Impact factor: 3.914

2. CYLD downregulates Livin and synergistically improves gemcitabine chemosensitivity and decreases migratory/invasive potential in bladder cancer: the effect is autophagy-associated.

Authors: Lei Yin; Shuai Liu; Chensheng Li; Sentai Ding; Dongbin Bi; Zhihong Niu; Liping Han; Wenjia Li; Dexuan Gao; Zheng Liu; Jiaju Lu
Journal: Tumour Biol Date: 2016-07-22

3. Silencing Livin induces apoptotic and autophagic cell death, increasing chemotherapeutic sensitivity to cisplatin of renal carcinoma cells.

Authors: Zhiyang Wang; Shuai Liu; Kejia Ding; Sentai Ding; Chensheng Li; Jiaju Lu; Dexuan Gao; Tong Zhang; Dongbin Bi
Journal: Tumour Biol Date: 2016-09-27

4. Birc7: A Late Fiber Gene of the Crystalline Lens.

Authors: Alicia De Maria; Steven Bassnett
Journal: Invest Ophthalmol Vis Sci Date: 2015-07 Impact factor: 4.799

5. Expression and prognostic significance of livin/BIRC7 in childhood acute lymphoblastic leukemia.

Authors: Lamia Ibrahim; Doaa Aladle; Ahmed Mansour; Ayman Hammad; Angi Adel Al Wakeel; Suzy A Abd El-Hameed
Journal: Med Oncol Date: 2014-04-03 Impact factor: 3.064

6. Expression of the apoptosis inhibitor livin in colorectal adenoma-carcinoma sequence: correlations with pathology and outcome.

Authors: Y Wang; Y Li; B Zhou; W Y Zhang; J T Guan; R Wang; L Yang; Q J Xia; Z G Zhou; X F Sun
Journal: Tumour Biol Date: 2014-10-23

7. Apoptosis inhibition or inflammation: the role of NAIP protein expression in Hodgkin and non-Hodgkin lymphomas compared to non-neoplastic lymph node.

Authors: Safoura Mazrouei; Amin Ziaei; Amir Pouya Tanhaee; Kianoosh Keyhanian; Mahdad Esmaeili; Azar Baradaran; Mansoor Salehi
Journal: J Inflamm (Lond) Date: 2012-02-23 Impact factor: 4.981