Literature DB >> 21614672

Thyroid hormone action in metabolic regulation.

Yiyun Song1, Xuan Yao, Hao Ying.   

Abstract

Thyroid hormone plays pivotal roles in growth, differentiation, development and metabolic homeostasis via thyroid hormone receptors (TRs) by controlling the expression of TR target genes. The transcriptional activity of TRs is modulated by multiple factors including various TR isoforms, diverse thyroid hormone response elements, different heterodimeric partners, coregulators, and the cellular location of TRs. In the present review, we summarize recent advance in understanding the molecular mechanisms of thyroid hormone action obtained from human subject research, thyroid hormone mimetics application, TR isoform-specific knock-in mouse models, and mitochondrion study with highlights in metabolic regulations. Finally, as future perspectives, we share our thoughts about current challenges and possible approaches to promote our knowledge of thyroid hormone action in metabolism.

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Year:  2011        PMID： 21614672      PMCID： PMC4875336          DOI： 10.1007/s13238-011-1046-x

Source DB:  PubMed          Journal:  Protein Cell        ISSN： 1674-800X            Impact factor:   14.870


  89 in total

1.  The c-erb-A protein is a high-affinity receptor for thyroid hormone.

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Journal:  Nature       Date:  1986 Dec 18-31       Impact factor: 49.962

2.  Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase.

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Journal:  Cell       Date:  1997-05-02       Impact factor: 41.582

3.  Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene.

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Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

4.  Insulin action in adipose tissue and muscle in hypothyroidism.

Authors:  George Dimitriadis; Panayota Mitrou; Vaia Lambadiari; Eleni Boutati; Eirini Maratou; Demosthenes B Panagiotakos; Efi Koukkou; Marinela Tzanela; Nikos Thalassinos; Sotirios A Raptis
Journal:  J Clin Endocrinol Metab       Date:  2006-09-26       Impact factor: 5.958

5.  Behavioral inhibition and impaired spatial learning and memory in hypothyroid mice lacking thyroid hormone receptor alpha.

Authors:  Jennifer Slone Wilcoxon; Gregory J Nadolski; Jacques Samarut; Olivier Chassande; Eva E Redei
Journal:  Behav Brain Res       Date:  2006-11-28       Impact factor: 3.332

6.  Differential sensitivity of thyroid hormone receptor isoform homodimers and mutant heterodimers to hormone-induced dissociation from deoxyribonucleic acid: its role in dominant negative action.

Authors:  X G Zhu; P McPhie; S Y Cheng
Journal:  Endocrinology       Date:  1997-04       Impact factor: 4.736

7.  Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis.

Authors:  Miriam O Ribeiro; Suzy D C Bianco; Masahiro Kaneshige; James J Schultz; Sheue-yann Cheng; Antonio C Bianco; Gregory A Brent
Journal:  Endocrinology       Date:  2009-11-11       Impact factor: 4.736

8.  Isoform-specific thyroid hormone receptor antibodies detect multiple thyroid hormone receptors in rat and human pituitaries.

Authors:  P M Yen; M E Sunday; D S Darling; W W Chin
Journal:  Endocrinology       Date:  1992-03       Impact factor: 4.736

9.  A mitochondrial protein compendium elucidates complex I disease biology.

Authors:  David J Pagliarini; Sarah E Calvo; Betty Chang; Sunil A Sheth; Scott B Vafai; Shao-En Ong; Geoffrey A Walford; Canny Sugiana; Avihu Boneh; William K Chen; David E Hill; Marc Vidal; James G Evans; David R Thorburn; Steven A Carr; Vamsi K Mootha
Journal:  Cell       Date:  2008-07-11       Impact factor: 41.582

10.  Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbA alpha 2 and peroxisome proliferator-activated receptor: evidence for different mechanisms of inhibition.

Authors:  S C Meier-Heusler; X Zhu; C Juge-Aubry; A Pernin; A G Burger; S Y Cheng; C A Meier
Journal:  Mol Cell Endocrinol       Date:  1995-01       Impact factor: 4.102
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  18 in total

Review 1.  Role of nuclear receptors in blastocyst implantation.

Authors:  Y M Vasquez; F J DeMayo
Journal:  Semin Cell Dev Biol       Date:  2013-08-28       Impact factor: 7.727

2.  Changes of activity and kinetics of certain liver and heart enzymes of hypothyroid and T(3)-treated rats.

Authors:  Urszula Czyzewska; Adam Tylicki; Magdalena Siemieniuk; Slawomir Strumilo
Journal:  J Physiol Biochem       Date:  2012-01-25       Impact factor: 4.158

Review 3.  Emerging roles of the corepressors NCoR1 and SMRT in homeostasis.

Authors:  Adrienne Mottis; Laurent Mouchiroud; Johan Auwerx
Journal:  Genes Dev       Date:  2013-04-15       Impact factor: 11.361

4.  Circadian regulation of Tshb gene expression by Rev-Erbα (NR1D1) and nuclear corepressor 1 (NCOR1).

Authors:  Irene O Aninye; Shunichi Matsumoto; Aniket R Sidhaye; Fredric E Wondisford
Journal:  J Biol Chem       Date:  2014-05-02       Impact factor: 5.157

5.  A cardiac microRNA governs systemic energy homeostasis by regulation of MED13.

Authors:  Chad E Grueter; Eva van Rooij; Brett A Johnson; Susan M DeLeon; Lillian B Sutherland; Xiaoxia Qi; Laurent Gautron; Joel K Elmquist; Rhonda Bassel-Duby; Eric N Olson
Journal:  Cell       Date:  2012-04-27       Impact factor: 41.582

6.  Atom-based 3D-QSAR, molecular docking and molecular dynamics simulation assessment of inhibitors for thyroid hormone receptor α and β.

Authors:  Manish Kumar Gupta; Krishna Misra
Journal:  J Mol Model       Date:  2014-06-05       Impact factor: 1.810

7.  Effects of central FGF21 infusion on the hypothalamus-pituitary-thyroid axis and energy metabolism in rats.

Authors:  Umit Yilmaz; Suat Tekin; Mehmet Demir; Yilmaz Cigremis; Suleyman Sandal
Journal:  J Physiol Sci       Date:  2018-02-07       Impact factor: 2.781

Review 8.  Role of microRNA in metabolic shift during heart failure.

Authors:  Mark V Pinti; Quincy A Hathaway; John M Hollander
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-10-14       Impact factor: 4.733

9.  Engineering triiodothyronine (T3) nanoparticle for use in ischemic brain stroke.

Authors:  Alexander Mdzinarishvili; Vijaykumar Sutariya; Phani K Talasila; Werner J Geldenhuys; Prabodh Sadana
Journal:  Drug Deliv Transl Res       Date:  2013-08       Impact factor: 4.617

10.  Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA.

Authors:  Cristina Aguayo-Mazzucato; Ann Marie Zavacki; Alejandra Marinelarena; Jennifer Hollister-Lock; Ilham El Khattabi; Alessandro Marsili; Gordon C Weir; Arun Sharma; P Reed Larsen; Susan Bonner-Weir
Journal:  Diabetes       Date:  2013-01-10       Impact factor: 9.461
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