Literature DB >> 21614641

Further insights into the characterization of equine adipose tissue-derived mesenchymal stem cells.

Oksana Raabe1, Katja Shell, Antonia Würtz, Christine Maria Reich, Sabine Wenisch, Stefan Arnhold.   

Abstract

Adipose tissue-derived stem cells (ADSCs) represent a promising subpopulation of adult stem cells for tissue engineering applications in veterinary medicine. In this study we focused on the morphological and molecular biological properties of the ADSCs. The expression of stem cell markers Oct4, Nanog and the surface markers CD90 and CD105 were detected using RT-PCR. ADSCs showed a proliferative potential and were capable of adipogenic and osteogenic differentiation. Expression of Alkaline phosphatase (AP), phosphoprotein (SPP1), Runx2 and osteocalcin (OC) mRNA were positive in osteogenic lineages and peroxisome proliferator activated receptor (Pparγ2) mRNA was positive in adipogenic lineages. ADSCs show stem cell and surface marker profiles and differentiation characteristics that are similar to but distinct from other adult stem cells, such as bone marrow-derived mesenchymal stem cells (BM-MSCs). The availability of an easily accessible and reproducible cell source may greatly facilitate the development of stem cell based tissue engineering and therapies for regenerative equine medicine.

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Year:  2011        PMID： 21614641     DOI： 10.1007/s11259-011-9480-z

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  33 in total

1.  Dissimilar differentiation of mesenchymal stem cells from bone marrow, umbilical cord blood, and adipose tissue.

Authors:  C K Rebelatto; A M Aguiar; M P Moretão; A C Senegaglia; P Hansen; F Barchiki; J Oliveira; J Martins; C Kuligovski; F Mansur; A Christofis; V F Amaral; P S Brofman; S Goldenberg; L S Nakao; A Correa
Journal:  Exp Biol Med (Maywood)       Date:  2008-04-29

2.  Isolation, characterization, and differentiation potential of canine adipose-derived stem cells.

Authors:  N M Vieira; V Brandalise; E Zucconi; M Secco; B E Strauss; M Zatz
Journal:  Cell Transplant       Date:  2009-12-08       Impact factor: 4.064

Review 3.  Markers of stemness in equine mesenchymal stem cells: a plea for uniformity.

Authors:  Catharina De Schauwer; Evelyne Meyer; Gerlinde R Van de Walle; Ann Van Soom
Journal:  Theriogenology       Date:  2010-12-31       Impact factor: 2.740

Review 4.  Basic science and clinical application of stem cells in veterinary medicine.

Authors:  I Ribitsch; J Burk; U Delling; C Geißler; C Gittel; H Jülke; W Brehm
Journal:  Adv Biochem Eng Biotechnol       Date:  2010       Impact factor: 2.635

5.  Osteogenic potential of human adipose tissue-derived stromal cells as an alternative stem cell source.

Authors:  Hidemi Hattori; Masato Sato; Kazunori Masuoka; Miya Ishihara; Toshiyuki Kikuchi; Takemi Matsui; Bonpei Takase; Toshiaki Ishizuka; Makoto Kikuchi; Kyosuke Fujikawa; Masayuki Ishihara
Journal:  Cells Tissues Organs       Date:  2004       Impact factor: 2.481

6.  Characterization and differentiation of equine umbilical cord-derived matrix cells.

Authors:  Steven M Hoynowski; Madeline M Fry; Bryn M Gardner; Matthew T Leming; Jeanell R Tucker; Linda Black; Theodore Sand; Kathy E Mitchell
Journal:  Biochem Biophys Res Commun       Date:  2007-08-13       Impact factor: 3.575

7.  Stem cells from the fat tissue of rabbits: an easy-to-find experimental source.

Authors:  Fabrício Carvalho Torres; Consuelo Junqueira Rodrigues; Ithamar Nogueira Stocchero; Marcus Castro Ferreira
Journal:  Aesthetic Plast Surg       Date:  2007 Sep-Oct       Impact factor: 2.326

Review 8.  Recent progress on tissue-resident adult stem cell biology and their therapeutic implications.

Authors:  Murielle Mimeault; Surinder K Batra
Journal:  Stem Cell Rev       Date:  2008       Impact factor: 5.739

Review 9.  Stem cells in veterinary medicine--attempts at regenerating equine tendon after injury.

Authors:  Lucy E Richardson; Jayesh Dudhia; Peter D Clegg; Roger Smith
Journal:  Trends Biotechnol       Date:  2007-08-09       Impact factor: 19.536

10.  Horse bone marrow mesenchymal stem cells express embryo stem cell markers and show the ability for tenogenic differentiation by in vitro exposure to BMP-12.

Authors:  Stefania Violini; Paola Ramelli; Laura F Pisani; Chiara Gorni; Paola Mariani
Journal:  BMC Cell Biol       Date:  2009-04-22       Impact factor: 4.241
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  10 in total

Review 1.  Adipose tissue derived mesenchymal stem cells for musculoskeletal repair in veterinary medicine.

Authors:  Stefan Arnhold; Sabine Wenisch
Journal:  Am J Stem Cells       Date:  2015-03-15

2.  Evaluation of adipose-derived stromal vascular fraction from the lateral tailhead, inguinal region, and mesentery of horses.

Authors:  Garrett L Metcalf; Scott R McClure; Jesse M Hostetter; Rudy F Martinez; Chong Wang
Journal:  Can J Vet Res       Date:  2016-10       Impact factor: 1.310

3.  Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro.

Authors:  O Raabe; K Shell; A Goessl; C Crispens; Y Delhasse; A Eva; G Scheiner-Bobis; S Wenisch; S Arnhold
Journal:  Am J Stem Cells       Date:  2013-03-08

4.  Isolation, culture and chondrogenic differentiation of canine adipose tissue- and bone marrow-derived mesenchymal stem cells--a comparative study.

Authors:  Christine M Reich; Oksana Raabe; Sabine Wenisch; Philip S Bridger; Martin Kramer; Stefan Arnhold
Journal:  Vet Res Commun       Date:  2012-03-04       Impact factor: 2.459

5.  Phenotypic and immunomodulatory properties of equine cord blood-derived mesenchymal stromal cells.

Authors:  Laurence Tessier; Dorothee Bienzle; Lynn B Williams; Thomas G Koch
Journal:  PLoS One       Date:  2015-04-22       Impact factor: 3.240

6.  Investigation of stemness and multipotency of equine adipose-derived mesenchymal stem cells (ASCs) from different fat sources in comparison with lipoma.

Authors:  Stefan Arnhold; Mohamed I Elashry; Michele C Klymiuk; Florian Geburek
Journal:  Stem Cell Res Ther       Date:  2019-10-22       Impact factor: 6.832

7.  Combined macromolecule biomaterials together with fluid shear stress promote the osteogenic differentiation capacity of equine adipose-derived mesenchymal stem cells.

Authors:  Mohamed I Elashry; Nadine Baulig; Alena-Svenja Wagner; Michele C Klymiuk; Benjamin Kruppke; Thomas Hanke; Sabine Wenisch; Stefan Arnhold
Journal:  Stem Cell Res Ther       Date:  2021-02-12       Impact factor: 6.832

8.  Effect of hypoxia on equine mesenchymal stem cells derived from bone marrow and adipose tissue.

Authors:  Beatriz Ranera; Ana Rosa Remacha; Samuel Álvarez-Arguedas; Antonio Romero; Francisco José Vázquez; Pilar Zaragoza; Inmaculada Martín-Burriel; Clementina Rodellar
Journal:  BMC Vet Res       Date:  2012-08-22       Impact factor: 2.741

9.  Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue.

Authors:  Sun-A Ock; Raghavendra Baregundi Subbarao; Yeon-Mi Lee; Jeong-Hyeon Lee; Ryoung-Hoon Jeon; Sung-Lim Lee; Ji Kwon Park; Sun-Chul Hwang; Gyu-Jin Rho
Journal:  Stem Cells Int       Date:  2015-12-21       Impact factor: 5.443

10.  Isolation of equine multipotent mesenchymal stromal cells by enzymatic tissue digestion or explant technique: comparison of cellular properties.

Authors:  Claudia Gittel; Walter Brehm; Janina Burk; Henriette Juelke; Carsten Staszyk; Iris Ribitsch
Journal:  BMC Vet Res       Date:  2013-10-29       Impact factor: 2.741
  10 in total

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