Literature DB >> 21614387

Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging.

Marc Vendrell1, Animesh Samanta, Seong-Wook Yun, Young-Tae Chang.   

Abstract

We report the synthesis and characterization of a novel NIR fluorescent deoxyglucose analogue, CyNE 2-DG. Experiments in different cell lines showed a preferential uptake of CyNE 2-DG in cancer cells and its effective competition with unlabeled d-glucose. Cell imaging experiments demonstrated the superior cell-permeability of CyNE 2-DG over the NIR standard IRDye 800CW 2-DG, and validated its application for cancer cell imaging in the NIR region.

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Year:  2011        PMID： 21614387     DOI： 10.1039/c1ob05519d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  10 in total

1.  Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell fluorescence imaging.

Authors:  Lorena Mendive-Tapia; Ramon Subiros-Funosas; Can Zhao; Fernando Albericio; Nick D Read; Rodolfo Lavilla; Marc Vendrell
Journal:  Nat Protoc       Date:  2017-07-13       Impact factor: 13.491

Review 2.  The sweet spot: FDG and other 2-carbon glucose analogs for multi-modal metabolic imaging of tumor metabolism.

Authors:  Benjamin L Cox; Thomas R Mackie; Kevin W Eliceiri
Journal:  Am J Nucl Med Mol Imaging       Date:  2014-12-15

3.  Ultra Pseudo-Stokes Shift Near Infrared Dyes Based on Energy Transfer.

Authors:  Junyan Han; Anthony Engler; Jianjun Qi; Ching-Hsuan Tung
Journal:  Tetrahedron Lett       Date:  2013-02-06       Impact factor: 2.415

Review 4.  Visualizing sweetness: increasingly diverse applications for fluorescent-tagged glucose bioprobes and their recent structural modifications.

Authors:  Woong Hee Kim; Jinho Lee; Da-Woon Jung; Darren R Williams
Journal:  Sensors (Basel)       Date:  2012-04-18       Impact factor: 3.576

5.  A fluorescent activatable probe for imaging intracellular Mg2+ .

Authors:  Ryan Treadwell; Fabio de Moliner; Ramon Subiros-Funosas; Toby Hurd; Kirsten Knox; Marc Vendrell
Journal:  Org Biomol Chem       Date:  2018-01-03       Impact factor: 3.876

6.  Probing binding specificity of the sucrose transporter AtSUC2 with fluorescent coumarin glucosides.

Authors:  Fabio De Moliner; Kirsten Knox; Anke Reinders; John M Ward; Paul J McLaughlin; Karl Oparka; Marc Vendrell
Journal:  J Exp Bot       Date:  2018-04-27       Impact factor: 6.992

7.  Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplets.

Authors:  Fabio de Moliner; Aaron King; Gleiston G Dias; Guilherme F de Lima; Carlos A de Simone; Eufrânio N da Silva Júnior; Marc Vendrell
Journal:  Front Chem       Date:  2018-08-13       Impact factor: 5.221

8.  A deep-red fluorescent molecular rotor based on donor-two-acceptor modular system for imaging mitochondrial viscosity.

Authors:  Xiaoxi Yin; Yiping Cai; Songtao Cai; Xiaojie Jiao; Chang Liu; Song He; Xianshun Zeng
Journal:  RSC Adv       Date:  2020-08-20       Impact factor: 3.361

9.  Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target.

Authors:  Heewon Cho; Haw-Young Kwon; Amit Sharma; Sun Hyeok Lee; Xiao Liu; Naoki Miyamoto; Jong-Jin Kim; Sin-Hyeog Im; Nam-Young Kang; Young-Tae Chang
Journal:  Nat Commun       Date:  2022-10-10       Impact factor: 17.694

10.  Tricarbocyanine N-triazoles: the scaffold-of-choice for long-term near-infrared imaging of immune cells in vivo.

Authors:  Richard J Mellanby; Jamie I Scott; Iris Mair; Antonio Fernandez; Louise Saul; Jochen Arlt; Monica Moral; Marc Vendrell
Journal:  Chem Sci       Date:  2018-08-08       Impact factor: 9.825
  10 in total

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