Reusable plasmonic aptasensors: using a single nanoparticle to establish a calibration curve and to detect analytes.

We demonstrate plasmonic aptasensors that allow a single nanoparticle (NP) to generate a calibration curve and to detect analytes. The proposed reusable aptasensors have significant advantages over conventional single-NP based assays in terms of sensitivity and reproducibility. This journal is © The Royal Society of Chemistry 2011