Literature DB >> 21612288

Total synthesis of unguisin A.

Luke Hunter1, Jonathan H Chung.   

Abstract

The first synthesis of the γ-aminobutyric acid (GABA)-containing cyclic heptapeptide unguisin A is reported, confirming the structure of this natural product. Macrocyclization of a flexible GABA-containing linear precursor is found to proceed rapidly and in good yield.

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Year:  2011        PMID： 21612288     DOI： 10.1021/jo200813a

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

Review 1.  Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

Authors:  Vedanjali Gogineni; Mark T Hamann
Journal:  Biochim Biophys Acta Gen Subj       Date:  2017-08-24       Impact factor: 3.770

2.  One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes.

Authors:  Vladimir A Maslivetc; Marina Rubina; Michael Rubin
Journal:  Org Biomol Chem       Date:  2015-08-05       Impact factor: 3.876

3.  Electrostatically induced pKa shifts in oligopeptides: the upshot of neighboring side chains.

Authors:  Amir Norouzy; Alexandra I Lazar; Mohammad Hossein Karimi-Jafari; Rohoullah Firouzi; Werner M Nau
Journal:  Amino Acids       Date:  2022-01-24       Impact factor: 3.520

4.  Depsidone Derivatives and a Cyclopeptide Produced by Marine Fungus Aspergillus unguis under Chemical Induction and by Its Plasma Induced Mutant.

Authors:  Wen-Cong Yang; Hai-Yan Bao; Ya-Yue Liu; Ying-Ying Nie; Jing-Ming Yang; Peng-Zhi Hong; Yi Zhang
Journal:  Molecules       Date:  2018-09-03       Impact factor: 4.411

Review 5.  Stereoselectively fluorinated N-heterocycles: a brief survey.

Authors:  Xiang-Guo Hu; Luke Hunter
Journal:  Beilstein J Org Chem       Date:  2013-11-29       Impact factor: 2.883
  5 in total

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