| Literature DB >> 2161055 |
K O Netzer1, A Rethwilm, B Maurer, V ter Meulen.
Abstract
We have identified the major immunogenic structural proteins of the human foamy virus (HFV), a distinct member of the foamy virus subfamily of Retroviridae. Radiolabelled viral proteins were immunoprecipitated from HFV-infected cells by foamy virus antisera of human and non-human primate origin. Precipitated viral proteins were in the range of 31K to 170K. Labelling of proteins with [14C]glucosamine or with [35S]methionine in the presence of tunicamycin, as well as endo-beta-N-acetylglycosaminidase H and F treatment of [35S]methionine-labelled proteins, revealed three viral glycoproteins of approximately 170K, 130K and 47K, most likely representing the env gene-encoded precursor, the surface glycoprotein and the transmembrane protein of HFV, respectively.Entities:
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Year: 1990 PMID: 2161055 DOI: 10.1099/0022-1317-71-5-1237
Source DB: PubMed Journal: J Gen Virol ISSN: 0022-1317 Impact factor: 3.891