Literature DB >> 2161055

Identification of the major immunogenic structural proteins of human foamy virus.

K O Netzer1, A Rethwilm, B Maurer, V ter Meulen.   

Abstract

We have identified the major immunogenic structural proteins of the human foamy virus (HFV), a distinct member of the foamy virus subfamily of Retroviridae. Radiolabelled viral proteins were immunoprecipitated from HFV-infected cells by foamy virus antisera of human and non-human primate origin. Precipitated viral proteins were in the range of 31K to 170K. Labelling of proteins with [14C]glucosamine or with [35S]methionine in the presence of tunicamycin, as well as endo-beta-N-acetylglycosaminidase H and F treatment of [35S]methionine-labelled proteins, revealed three viral glycoproteins of approximately 170K, 130K and 47K, most likely representing the env gene-encoded precursor, the surface glycoprotein and the transmembrane protein of HFV, respectively.

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Year:  1990        PMID: 2161055     DOI: 10.1099/0022-1317-71-5-1237

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  26 in total

1.  RNA and protein requirements for incorporation of the Pol protein into foamy virus particles.

Authors:  Katrin Peters; Tatiana Wiktorowicz; Martin Heinkelein; Axel Rethwilm
Journal:  J Virol       Date:  2005-06       Impact factor: 5.103

2.  Carboxy-terminal cleavage of the human foamy virus Gag precursor molecule is an essential step in the viral life cycle.

Authors:  J Enssle; N Fischer; A Moebes; B Mauer; U Smola; A Rethwilm
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

3.  Characterization of a human foamy virus 170-kilodalton Env-Bet fusion protein generated by alternative splicing.

Authors:  D Lindemann; A Rethwilm
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

Review 4.  Foamy viruses are unconventional retroviruses.

Authors:  M L Linial
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

5.  A sorting motif localizes the foamy virus glycoprotein to the endoplasmic reticulum.

Authors:  P A Goepfert; K L Shaw; G D Ritter; M J Mulligan
Journal:  J Virol       Date:  1997-01       Impact factor: 5.103

6.  Expression and maturation of human foamy virus Gag precursor polypeptides.

Authors:  M L Giron; S Colas; J Wybier; F Rozain; R Emanoil-Ravier
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

7.  Mucosal and systemic antibody responses in humans infected with simian foamy virus.

Authors:  James E Cummins; Roumiana S Boneva; William M Switzer; Logan L Christensen; Paul Sandstrom; Walid Heneine; Louisa E Chapman; Charlene S Dezzutti
Journal:  J Virol       Date:  2005-10       Impact factor: 5.103

8.  Active foamy virus proteinase is essential for virus infectivity but not for formation of a Pol polyprotein.

Authors:  J Konvalinka; M Löchelt; H Zentgraf; R M Flügel; H G Kräusslich
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Functional analysis of human foamy virus accessory reading frames.

Authors:  G Baunach; B Maurer; H Hahn; M Kranz; A Rethwilm
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

10.  Search for retrovirus in the chronic fatigue syndrome.

Authors:  J W Gow; K Simpson; A Schliephake; W M Behan; L J Morrison; H Cavanagh; A Rethwilm; P O Behan
Journal:  J Clin Pathol       Date:  1992-12       Impact factor: 3.411

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