BACKGROUND: Screening for blunt carotid and vertebral injury (BCVI) is increasing without a clear understanding of whether the chosen screening approach is cost-effective. We hypothesized that screening for BCVI using computed tomography angiography (CTA) was cost-effective in populations at high risk for BCVI. METHODS: A decision analysis was performed modeling current BCVI screening approaches: no screening, duplex ultrasound, magnetic resonance angiography, angiography, and CTA. Treatment options included antiplatelet therapy, anticoagulation, stents for pseudoaneurysm, and no treatment. Probability estimates for incidence of injury and stroke, sensitivity and specificity of the screening modality, and type of treatment were taken from published data. Average wholesale price and medicare reimbursement costs were used. Two populations were analyzed; high-risk and overall blunt trauma populations. Two perspectives were taken; societal (including lifetime stroke costs) and institutional (ignoring lifetime stroke costs). RESULTS: In the high-risk population, from a societal perspective, CTA has the lowest cost and stroke rate; $3,727 per patient screened with a 1% stroke rate. No treatment has the highest cost and stroke rate. From an institutional perspective, no screening is the least costly option but has an 11% stroke rate. Duplex ultrasound is the most cost-effective screening modality; $8,940 per stroke prevented. CONCLUSION: From the societal perspective, CTA is the most cost-effective screening strategy for patients at high risk for BCVI. From an institutional perspective, CTA prevents the most strokes at a reasonable cost.
BACKGROUND: Screening for blunt carotid and vertebral injury (BCVI) is increasing without a clear understanding of whether the chosen screening approach is cost-effective. We hypothesized that screening for BCVI using computed tomography angiography (CTA) was cost-effective in populations at high risk for BCVI. METHODS: A decision analysis was performed modeling current BCVI screening approaches: no screening, duplex ultrasound, magnetic resonance angiography, angiography, and CTA. Treatment options included antiplatelet therapy, anticoagulation, stents for pseudoaneurysm, and no treatment. Probability estimates for incidence of injury and stroke, sensitivity and specificity of the screening modality, and type of treatment were taken from published data. Average wholesale price and medicare reimbursement costs were used. Two populations were analyzed; high-risk and overall blunt trauma populations. Two perspectives were taken; societal (including lifetime stroke costs) and institutional (ignoring lifetime stroke costs). RESULTS: In the high-risk population, from a societal perspective, CTA has the lowest cost and stroke rate; $3,727 per patient screened with a 1% stroke rate. No treatment has the highest cost and stroke rate. From an institutional perspective, no screening is the least costly option but has an 11% stroke rate. Duplex ultrasound is the most cost-effective screening modality; $8,940 per stroke prevented. CONCLUSION: From the societal perspective, CTA is the most cost-effective screening strategy for patients at high risk for BCVI. From an institutional perspective, CTA prevents the most strokes at a reasonable cost.
Authors: Megan M Lockwood; Gabriel A Smith; Joseph Tanenbaum; Daniel Lubelski; Andreea Seicean; Jonathan Pace; Edward C Benzel; Thomas E Mroz; Michael P Steinmetz Journal: J Neurosurg Spine Date: 2015-11-27
Authors: Vijay M Ravindra; Robert J Bollo; Walavan Sivakumar; Hassan Akbari; Robert P Naftel; David D Limbrick; Andrew Jea; Stephen Gannon; Chevis Shannon; Yekaterina Birkas; George L Yang; Colin T Prather; John R Kestle; Jay Riva-Cambrin Journal: J Neurotrauma Date: 2016-07-25 Impact factor: 5.269
Authors: Dennis Hundersmarck; Willem-Bart M Slooff; Jelle F Homans; Quirine M J van der Vliet; Nizar Moayeri; Falco Hietbrink; Gert J de Borst; Fetullah Cumhur Öner; Sander P J Muijs; Luke P H Leenen Journal: Eur J Trauma Emerg Surg Date: 2019-06-13 Impact factor: 3.693