| Literature DB >> 2161036 |
H Kikuta1, H Lu, K Tomizawa, S Matsumoto.
Abstract
The effect of monoclonal antibody to CD3 on human herpesvirus 6 (HHV-6) replication was assessed in adult peripheral blood mononuclear cells (PBMC) and in cord blood mononuclear cells (CBMC) by anticomplement immunofluorescence and Southern blot hybridization. Infection of CBMC by HHV-6 was productive; however, little or no infection was observed with PBMC from adults exposed to the virus even if stimulated by phytohemagglutinin. Monoclonal antibody to CD3 strongly enhanced HHV-6 replicative cycles in PBMC from adults.Entities:
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Year: 1990 PMID： 2161036 DOI： 10.1093/infdis/161.6.1085
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226