Literature DB >> 21608

The genetic and biochemical properties of the D-amino acid oxidases in human tissues.

R F Barker, D A Hopkinson.   

Abstract

1. Two distinct forms of oxidases catalysing the oxidative deamidation of D-alpha-amino acids have been identified in human tissues: D-amino acid oxidase (DAMOX) and D-aspartate oxidase (DASOX). 2. The enzymes differ in their electrophoretic properties, tissue distribution, binding with flavine adenine denucleotide, heat stability, molecular size and possibly in subunit structure. 3. Neither enzyme exhibits genetic polymorphism in European populations, but a rare electrophoretic variant phenotype (DASOX 2-1) was identified which suggests that the DASOX locus is autosomal and independent of the DAMOX locus.

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Year:  1977        PMID: 21608     DOI: 10.1111/j.1469-1809.1977.tb01959.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  8 in total

1.  Detection after electrophoresis of enzymes involved in ammonia metabolism using L-glutamate dehydrogenase as a linking enzyme.

Authors:  R L Nelson; S Povey; D A Hopkinson; H Harris
Journal:  Biochem Genet       Date:  1977-12       Impact factor: 1.890

2.  Spatiotemporal localization of D-amino acid oxidase and D-aspartate oxidases during development in Caenorhabditis elegans.

Authors:  Yasuaki Saitoh; Masumi Katane; Tomonori Kawata; Kazuhiro Maeda; Masae Sekine; Takemitsu Furuchi; Hiroyuki Kobuna; Taro Sakamoto; Takao Inoue; Hiroyuki Arai; Yasuhito Nakagawa; Hiroshi Homma
Journal:  Mol Cell Biol       Date:  2012-03-05       Impact factor: 4.272

3.  Studies of D-amino acid oxidase activity in human epidermis and cultured human epidermal cells.

Authors:  P K Jensen; N O Jacobsen
Journal:  Arch Dermatol Res       Date:  1984       Impact factor: 3.017

4.  Liquid chromatographic determination of D-amino acids in cheese and cow milk. Implication of starter cultures, amino acid racemases, and rumen microorganisms on formation, and nutritional considerations.

Authors:  H Brückner; P Jaek; M Langer; H Godel
Journal:  Amino Acids       Date:  1992-10       Impact factor: 3.520

Review 5.  The neurobiology of D-amino acid oxidase and its involvement in schizophrenia.

Authors:  L Verrall; P W J Burnet; J F Betts; P J Harrison
Journal:  Mol Psychiatry       Date:  2009-09-29       Impact factor: 15.992

6.  D-Amino acids in chronic renal failure and the effects of dialysis and urinary losses.

Authors:  G A Young; S Kendall; A M Brownjohn
Journal:  Amino Acids       Date:  1994-10       Impact factor: 3.520

7.  Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians.

Authors:  Paolo Piaggi; Çiğdem Köroğlu; Anup K Nair; Jeff Sutherland; Yunhua L Muller; Pankaj Kumar; Wen-Chi Hsueh; Sayuko Kobes; Alan R Shuldiner; Hye In Kim; Nehal Gosalia; Cristopher V Van Hout; Marcus Jones; William C Knowler; Jonathan Krakoff; Robert L Hanson; Clifton Bogardus; Leslie J Baier
Journal:  J Clin Endocrinol Metab       Date:  2020-11-01       Impact factor: 5.958

Review 8.  Genetics of amyotrophic lateral sclerosis: an update.

Authors:  Sheng Chen; Pavani Sayana; Xiaojie Zhang; Weidong Le
Journal:  Mol Neurodegener       Date:  2013-08-13       Impact factor: 14.195

  8 in total

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