Literature DB >> 21607164

Purinergic signaling in the gastrointestinal tract.

Geoffrey Burnstock1.   

Abstract

Geoffrey Burnstock completed a BSc at King's College London and a PhD at University College London. He held postdoctoral fellowships with Wilhelm Feldberg (National Institute for Medical Research), Edith Bülbring (University of Oxford) and C. Ladd Prosser (University of Illinois). He was appointed to a Senior Lectureship in Melbourne University in 1959 and became Professor and Chairman of Zoology in 1964. In 1975 he became Head of Department of Anatomy and Developmental Biology at UCL and Convenor of the Center of Neuroscience. He has been Director of the Autonomic Neuroscience Institute at the Royal Free Hospital School of Medicine since 1997. He was elected to the Australian Academy of Sciences in 1971, the Royal Society in 1986, the Academy of Medical Sciences in 1998 and an Honorary Fellow of the Royal College of Surgeons and the Royal College of Physicians in 1999 and 2000. He was awarded the Royal Society Gold Medal in 2000. He is editor-in-chief of the journals Autonomic Neuroscience and Purinergic Signalling and on the editorial boards of many other journals. Geoffrey Burnstock's major research interest has been autonomic neurotransmission and he is best known for his seminal discovery of purinergic transmission and receptors, their signaling pathways and functional relevance. He has supervised over 100 PhD and MD students and published over 1400 original papers, re-views and books. He was first in the Institute of Scientific Information list of most cited scientists in Pharmacology and Toxicology from 1994-2004 [59.083 citations (March 2011) and an h-index of 109].

Entities:  

Keywords:  Gastrointestinal tract; Geoffrey Burnstock; Purinergic signaling

Year:  2011        PMID: 21607164      PMCID: PMC3097967          DOI: 10.4291/wjgp.v2.i2.31

Source DB:  PubMed          Journal:  World J Gastrointest Pathophysiol        ISSN: 2150-5330


  27 in total

Review 1.  Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction.

Authors:  G Burnstock
Journal:  J Anat       Date:  1999-04       Impact factor: 2.610

2.  The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves.

Authors:  P HOLTON
Journal:  J Physiol       Date:  1959-03-12       Impact factor: 5.182

Review 3.  Cellular distribution and functions of P2 receptor subtypes in different systems.

Authors:  Geoffrey Burnstock; Gillian E Knight
Journal:  Int Rev Cytol       Date:  2004

Review 4.  Pathophysiology and therapeutic potential of purinergic signaling.

Authors:  Geoffrey Burnstock
Journal:  Pharmacol Rev       Date:  2006-03       Impact factor: 25.468

5.  The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart.

Authors:  A N Drury; A Szent-Györgyi
Journal:  J Physiol       Date:  1929-11-25       Impact factor: 5.182

Review 6.  Physiology and pathophysiology of purinergic neurotransmission.

Authors:  Geoffrey Burnstock
Journal:  Physiol Rev       Date:  2007-04       Impact factor: 37.312

Review 7.  Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells.

Authors:  Geoffrey Burnstock
Journal:  Pharmacol Rep       Date:  2008 Jan-Feb       Impact factor: 3.024

Review 8.  The journey to establish purinergic signalling in the gut.

Authors:  G Burnstock
Journal:  Neurogastroenterol Motil       Date:  2008-05       Impact factor: 3.598

9.  Intrastriatal grafts of rat colonic smooth muscle lacking myenteric ganglia stimulate axonal sprouting and regeneration.

Authors:  E M Tew; P N Anderson; M J Saffrey; G Burnstock
Journal:  J Anat       Date:  1998-01       Impact factor: 2.610

Review 10.  Purine and pyrimidine receptors.

Authors:  G Burnstock
Journal:  Cell Mol Life Sci       Date:  2007-06       Impact factor: 9.261

View more
  5 in total

1.  β-Nicotinamide adenine dinucleotide acts at prejunctional adenosine A1 receptors to suppress inhibitory musculomotor neurotransmission in guinea pig colon and human jejunum.

Authors:  Guo-Du Wang; Xi-Yu Wang; Sumei Liu; Yun Xia; Fei Zou; Meihua Qu; Bradley J Needleman; Dean J Mikami; Jackie D Wood
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2015-03-26       Impact factor: 4.052

2.  S-nitrosylation inhibits pannexin 1 channel function.

Authors:  Alexander W Lohman; Janelle L Weaver; Marie Billaud; Joanna K Sandilos; Rachael Griffiths; Adam C Straub; Silvia Penuela; Norbert Leitinger; Dale W Laird; Douglas A Bayliss; Brant E Isakson
Journal:  J Biol Chem       Date:  2012-10-02       Impact factor: 5.157

Review 3.  The purinergic neurotransmitter revisited: a single substance or multiple players?

Authors:  Violeta N Mutafova-Yambolieva; Leonie Durnin
Journal:  Pharmacol Ther       Date:  2014-06-02       Impact factor: 12.310

Review 4.  Purinergic Ligands as Potential Therapeutic Tools for the Treatment of Inflammation-Related Intestinal Diseases.

Authors:  Diego Dal Ben; Luca Antonioli; Catia Lambertucci; Matteo Fornai; Corrado Blandizzi; Rosaria Volpini
Journal:  Front Pharmacol       Date:  2018-03-14       Impact factor: 5.810

Review 5.  Adenosine: Direct and Indirect Actions on Gastric Acid Secretion.

Authors:  Rosa M Arin; Adriana Gorostidi; Hiart Navarro-Imaz; Yuri Rueda; Olatz Fresnedo; Begoña Ochoa
Journal:  Front Physiol       Date:  2017-09-22       Impact factor: 4.566

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.