Literature DB >> 21606620

Inhibitory effect of topical maize glucosylceramide on skin photoaging in UVA-irradiated hairless mice.

Eriko Shimada1, Kazuhiko Aida, Tatsuya Sugawara, Takashi Hirata.   

Abstract

We investigated the effect of topical application of the glucosylceramide prepared from maize on photoaged mice. Six-week-old hairless female mice were swabbed on the back with glucosylceramide solution or vehicle, following UVA irradiation for 9 weeks. Wrinkle formation was evaluated at 3, 6, and 9 weeks by skin replica analysis by using a three-dimensional (3-D) imaging system. Moreover, epidermal thickness was analyzed at the end of the experiment. Topical application of glucosylceramide significantly reduced UVA-induced wrinkle formation in the skin as well as epidermal hypertrophy. These results suggest that topical glucosylceramide has an inhibitory effect on UVA-induced photoaging.

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Year:  2011        PMID： 21606620     DOI： 10.5650/jos.60.321

Source DB:  PubMed          Journal:  J Oleo Sci        ISSN： 1345-8957            Impact factor:   1.601


  6 in total

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Journal:  Cells       Date:  2020-02-24       Impact factor: 6.600

5.  The Protective Effect of Polyherbal Formulation, Harak Formula, on UVA-Induced Photoaging of Human Dermal Fibroblasts and Mouse Skin via Promoting Nrf2-Regulated Antioxidant Defense.

Authors:  Jinapath Lohakul; Anyamanee Chaiprasongsuk; Saowanee Jeayeng; Malinee Saelim; Phetthinee Muanjumpon; Saowalak Thanachaiphiwat; Pinpat Tripatara; Kittipong Soontrapa; Natchagorn Lumlerdkij; Pravit Akarasereenont; Uraiwan Panich
Journal:  Front Pharmacol       Date:  2021-04-12       Impact factor: 5.810

6.  Dietary ceramide 2-aminoethylphosphonate, a marine sphingophosphonolipid, improves skin barrier function in hairless mice.

Authors:  Nami Tomonaga; Yuki Manabe; Kazuhiko Aida; Tatsuya Sugawara
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  6 in total

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