Literature DB >> 21603515

Effective glycemic management in hospitalized patients: a multidisciplinary approach.

Margaret Bolton1, Anita Richard, Lawrence Blonde, Alan Burshell.   

Abstract

The dual purpose of this process paper is to describe the implementation of an intensive insulin infusion program against multiple barriers, despite the increasing evidence in the literature supporting glycemic control, and to report the glucose outcomes. Traditional hyperglycemic management has been done either by subcutaneous sliding scale or intravenous insulin infusions based on absolute glucose numbers. A review of the literature, with particular evidence within the cardiothoracic surgical (CTS) population, has shown significant deleterious effects of even mild hyperglycemia.Increasing evidence supporting prevention of hyperglycemia, along with an unsatisfactory review of current methods used in-house, prompted the initiation of a pilot program to improve current methods utilizing insulin therapy. A multidisciplinary committee was formed consisting of the director of the intensive care unit, a dietician, a nursing unit director, a charge nurse, an endocrinologist, and two endocrinology nurse practitioners with extensive experience in intensive insulin therapy, including continuous subcutaneous insulin infusion. A review of literature was performed to evaluate available data and intravenous insulin infusion algorithms used by published authors. The CTS population was chosen as well as the intensive care unit. Nursing barriers in particular were extensive, and the use of a velocity driven insulin protocol required didactic instruction as well as individual reinforcement. All education, algorithm development, and oversight of patients were primarily performed by the nurse practitioners with immediate endocrinologist availability if needed. A review of glucose results indicated a significant reduction in hyperglycemia with a decrease in hypoglycemia and facilitated transition to subcutaneous therapy when necessary.

Entities:  

Keywords:  cardiothoracic surgery; critical illness; hospital; hyperglycemia; hypoglycemia; insulin; multidisciplinary; protocol; slide rule

Year:  2007        PMID: 21603515      PMCID: PMC3096387     

Source DB:  PubMed          Journal:  Ochsner J        ISSN: 1524-5012


  15 in total

Review 1.  Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview.

Authors:  S E Capes; D Hunt; K Malmberg; P Pathak; H C Gerstein
Journal:  Stroke       Date:  2001-10       Impact factor: 7.914

Review 2.  Hyperglycemia in acutely ill patients.

Authors:  Victor M Montori; Bruce R Bistrian; M Molly McMahon
Journal:  JAMA       Date:  2002-11-06       Impact factor: 56.272

Review 3.  The rationale and management of hyperglycemia for in-patients with cardiovascular disease: time for change.

Authors:  Dace L Trence; Janet L Kelly; Irl B Hirsch
Journal:  J Clin Endocrinol Metab       Date:  2003-06       Impact factor: 5.958

Review 4.  Management of diabetes and hyperglycemia in hospitals.

Authors:  Stephen Clement; Susan S Braithwaite; Michelle F Magee; Andrew Ahmann; Elizabeth P Smith; Rebecca G Schafer; Irl B Hirsch; Irl B Hirsh
Journal:  Diabetes Care       Date:  2004-02       Impact factor: 19.112

5.  Improving inpatient diabetes care: nursing issues.

Authors:  Linda B Haas
Journal:  Endocr Pract       Date:  2006 Jul-Aug       Impact factor: 3.443

6.  Effects of insulin treatment on cause-specific one-year mortality and morbidity in diabetic patients with acute myocardial infarction. DIGAMI Study Group. Diabetes Insulin-Glucose in Acute Myocardial Infarction.

Authors:  K Malmberg; L Rydén; A Hamsten; J Herlitz; A Waldenström; H Wedel
Journal:  Eur Heart J       Date:  1996-09       Impact factor: 29.983

Review 7.  The effects of injury and sepsis on fuel utilization.

Authors:  S A Goldstein; D H Elwyn
Journal:  Annu Rev Nutr       Date:  1989       Impact factor: 11.848

8.  Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients.

Authors:  James Stephen Krinsley
Journal:  Mayo Clin Proc       Date:  2003-12       Impact factor: 7.616

9.  Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting.

Authors:  Anthony P Furnary; Guangqiang Gao; Gary L Grunkemeier; YingXing Wu; Kathryn J Zerr; Stephen O Bookin; H Storm Floten; Albert Starr
Journal:  J Thorac Cardiovasc Surg       Date:  2003-05       Impact factor: 5.209

10.  Implementation of a safe and effective insulin infusion protocol in a medical intensive care unit.

Authors:  Philip A Goldberg; Mark D Siegel; Robert S Sherwin; Joshua I Halickman; Michelle Lee; Valerie A Bailey; Sandy L Lee; James D Dziura; Silvio E Inzucchi
Journal:  Diabetes Care       Date:  2004-02       Impact factor: 19.112

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