Literature DB >> 21602981

Severe hypotension and water intoxication developed after an accidental oxytocin overdose in a morbidly obese patient undergoing cesarean section -A case report-.

Jang Hyeok In1, Jin Woo Choi, Hong Soo Jung, Jung-Ah Lee, Jin-Deok Joo, Dae-Woo Kim, Yeon Soo Jeon, Ju-Seon Park.   

Abstract

We present a 32-year-old, extremely obese, pregnant woman who developed severe hypotension and water intoxication after an accidental injection of large bolus of oxytocin during cesarean section under general anesthesia. The patient was initially thought to have an amniotic fluid embolism because of the abrupt hemodynamic changes developed immediately after fetal delivery and lack of recognition of medication error. It is highly recommended that careful attention should be paid not only to the possibility of hemodynamic deterioration and water intoxication if oxytocin is given rapidly in excessive doses, but to the confirmation of the proper use of the drug before it is injected.

Entities:  

Keywords:  Oxytocin; Water intoxication

Year:  2011        PMID: 21602981      PMCID: PMC3092966          DOI: 10.4097/kjae.2011.60.4.290

Source DB:  PubMed          Journal:  Korean J Anesthesiol        ISSN: 2005-6419


  10 in total

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Journal:  Br J Anaesth       Date:  2006-12-02       Impact factor: 9.166

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Journal:  Med J Aust       Date:  1980-01-12       Impact factor: 7.738

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7.  Haemodynamic changes caused by oxytocin during caesarean section under spinal anaesthesia.

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Journal:  Int J Obstet Anesth       Date:  2002-07       Impact factor: 2.603

8.  Neurologic sequelae after treatment of severe hyponatremia: a multicenter perspective.

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Journal:  J Am Soc Nephrol       Date:  1994-02       Impact factor: 10.121

Review 9.  Amniotic fluid embolism.

Authors:  Richard S Gist; Irene P Stafford; Andrew B Leibowitz; Yaakov Beilin
Journal:  Anesth Analg       Date:  2009-05       Impact factor: 5.108

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Authors:  S L Clark; G D Hankins; D A Dudley; G A Dildy; T F Porter
Journal:  Am J Obstet Gynecol       Date:  1995-04       Impact factor: 8.661

  10 in total
  6 in total

Review 1.  Oxytocin - a multifunctional analgesic for chronic deep tissue pain.

Authors:  Burel R Goodin; Timothy J Ness; Meredith T Robbins
Journal:  Curr Pharm Des       Date:  2015       Impact factor: 3.116

2.  Intravenous versus intramuscular prophylactic oxytocin for the third stage of labour.

Authors:  Olufemi T Oladapo; Babasola O Okusanya; Edgardo Abalos; Ioannis D Gallos; Argyro Papadopoulou
Journal:  Cochrane Database Syst Rev       Date:  2020-11-09

3.  A Case of Postpartum Pulmonary Edema Induced by Oxytocin.

Authors:  May Zaw; William Lim; Amber Latif
Journal:  Cureus       Date:  2021-11-15

Review 4.  Oxytocin for preventing postpartum haemorrhage (PPH) in non-facility birth settings.

Authors:  Tomas Pantoja; Edgardo Abalos; Evelina Chapman; Claudio Vera; Valentina P Serrano
Journal:  Cochrane Database Syst Rev       Date:  2016-04-14

Review 5.  Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour.

Authors:  Olufemi T Oladapo; Babasola O Okusanya; Edgardo Abalos
Journal:  Cochrane Database Syst Rev       Date:  2018-09-22

6.  ISIDOG Recommendations Concerning COVID-19 and Pregnancy.

Authors:  Francesca Donders; Risa Lonnée-Hoffmann; Aristotelis Tsiakalos; Werner Mendling; José Martinez de Oliveira; Philippe Judlin; Fengxia Xue; Gilbert G G Donders
Journal:  Diagnostics (Basel)       Date:  2020-04-22
  6 in total

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