Literature DB >> 21601677

The Eugene language for synthetic biology.

Lesia Bilitchenko1, Adam Liu, Douglas Densmore.   

Abstract

Synthetic biological systems are currently created by an ad hoc, iterative process of design, simulation, and assembly. These systems would greatly benefit from the introduction of a more formalized and rigorous specification of the desired system components as well as constraints on their composition. In order to do so, the creation of robust and efficient design flows and tools is imperative. We present a human readable language (Eugene) which allows for both the specification of synthetic biological designs based on biological parts as well as providing a very expressive constraint system to drive the creation of composite devices from collection of parts. This chapter provides an overview of the language primitives as well as instructions on installation and use of Eugene v0.03b.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21601677     DOI: 10.1016/B978-0-12-385120-8.00007-3

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN: 0076-6879            Impact factor:   1.600


  4 in total

1.  Towards the rational design of synthetic cells with prescribed population dynamics.

Authors:  Neil Dalchau; Matthew J Smith; Samuel Martin; James R Brown; Stephen Emmott; Andrew Phillips
Journal:  J R Soc Interface       Date:  2012-06-08       Impact factor: 4.118

2.  Eugene--a domain specific language for specifying and constraining synthetic biological parts, devices, and systems.

Authors:  Lesia Bilitchenko; Adam Liu; Sherine Cheung; Emma Weeding; Bing Xia; Mariana Leguia; J Christopher Anderson; Douglas Densmore
Journal:  PLoS One       Date:  2011-04-29       Impact factor: 3.240

Review 3.  Creating biological nanomaterials using synthetic biology.

Authors:  MaryJoe K Rice; Warren C Ruder
Journal:  Sci Technol Adv Mater       Date:  2013-12-03       Impact factor: 8.090

4.  2ab assembly: a methodology for automatable, high-throughput assembly of standard biological parts.

Authors:  Mariana Leguia; Jennifer An Brophy; Douglas Densmore; Angel Asante; J Christopher Anderson
Journal:  J Biol Eng       Date:  2013-01-10       Impact factor: 4.355

  4 in total

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