Youn-Jung Son1, Eun Kyeung Song. 1. Department of Nursing, College of Medicine, Soonchunhyang University 366-1, Ssangyong-dong, Cheonan 330-946, South Korea.
Abstract
BACKGROUND: Anxiety or depressive symptoms are known to be predictors of impaired health-related quality of life (HRQoL). However, little research has focused on the impact of type D personality as chronic psychological distress on HRQoL in atrial fibrillation (AF) patients. Increased high-sensitivity C-reactive protein (hsCRP) is likely to be associated with anxiety or depressive symptoms, whereas the relation of hsCRP to Type D personality was unexplored, and the impact of hsCRP on HRQoL was undetermined in AF patients. AIM: To determine whether type D personality and hsCRP are independently associated with impaired HRQoL. METHODS: A cross-sectional study design was used among a total of 114 patients with chronic AF. Patients underwent measurements of serum levels of hsCRP. Type D personality, anxiety and depressive symptoms, and HRQoL were assessed by the type D scale, the hospital anxiety and depression scale, and the short-form medical outcomes survey, respectively. Hierarchical linear regression was used to determine the impact of Type D personality and hsCRP on HRQoL. RESULTS: Thirty-two percent of patients had Type D personality. Patients with type D personality had higher hsCRP than those with non-type D personality (1.4 ± 1.9 vs. 0.6 ± 2.2, p = 0.046). In hierarchical linear regression, type D personality (β = - 0.28; p = 0.005) and hsCRP (β = -0.21; p = 0.034) were independently associated with HRQoL controlling for clinical risk factors, anxiety, and depression symptoms. CONCLUSIONS: Type D personality and hsCRP are independent predictors of impaired HRQoL. Clinicians need to pay attention to patients with Type D personality and monitor serum levels of hsCRP to prevent impaired HRQoL in AF patient.
BACKGROUND: Anxiety or depressive symptoms are known to be predictors of impaired health-related quality of life (HRQoL). However, little research has focused on the impact of type D personality as chronic psychological distress on HRQoL in atrial fibrillation (AF) patients. Increased high-sensitivity C-reactive protein (hsCRP) is likely to be associated with anxiety or depressive symptoms, whereas the relation of hsCRP to Type D personality was unexplored, and the impact of hsCRP on HRQoL was undetermined in AF patients. AIM: To determine whether type D personality and hsCRP are independently associated with impaired HRQoL. METHODS: A cross-sectional study design was used among a total of 114 patients with chronic AF. Patients underwent measurements of serum levels of hsCRP. Type D personality, anxiety and depressive symptoms, and HRQoL were assessed by the type D scale, the hospital anxiety and depression scale, and the short-form medical outcomes survey, respectively. Hierarchical linear regression was used to determine the impact of Type D personality and hsCRP on HRQoL. RESULTS: Thirty-two percent of patients had Type D personality. Patients with type D personality had higher hsCRP than those with non-type D personality (1.4 ± 1.9 vs. 0.6 ± 2.2, p = 0.046). In hierarchical linear regression, type D personality (β = - 0.28; p = 0.005) and hsCRP (β = -0.21; p = 0.034) were independently associated with HRQoL controlling for clinical risk factors, anxiety, and depression symptoms. CONCLUSIONS: Type D personality and hsCRP are independent predictors of impaired HRQoL. Clinicians need to pay attention to patients with Type D personality and monitor serum levels of hsCRP to prevent impaired HRQoL in AF patient.
Authors: Renate B Schnabel; Matthias Michal; Sandra Wilde; Jörg Wiltink; Philipp S Wild; Christoph R Sinning; Edith Lubos; Francisco M Ojeda; Tanja Zeller; Thomas Munzel; Stefan Blankenberg; Manfred E Beutel Journal: PLoS One Date: 2013-12-04 Impact factor: 3.240
Authors: Tomos E Walters; Kate Wick; Gabriel Tan; Megan Mearns; Stephen A Joseph; Joseph B Morton; Prashanthan Sanders; Christina Bryant; Peter M Kistler; Jonathan M Kalman Journal: J Am Heart Assoc Date: 2018-09-18 Impact factor: 5.501