Literature DB >> 21600898

Insight from genome-wide association studies in rheumatoid arthritis and multiple sclerosis.

Akari Suzuki1, Yuta Kochi, Yukinari Okada, Kazuhiko Yamamoto.   

Abstract

Autoimmune diseases are caused by multiple genes and environmental effects. In addition, genetic contributions and the number of associated genes differ among different diseases and ethnic populations. Genome-wide association studies (GWAS) on rheumatoid arthritis (RA) and multiple sclerosis (MS) show that these diseases share many genetic factors. Recently, in addition to the major histocompatibility complex (MHC) gene, other genetic loci have been found to be associated with the risk for autoimmune diseases. This review focuses on the search for genetic variants that influence the susceptibility to RA and MS as typical autoimmune diseases and discusses the future of GWAS.
Copyright © 2011 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 21600898     DOI： 10.1016/j.febslet.2011.05.025

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  16 in total

Review 1.  Innate lymphoid cells in autoimmunity: emerging regulators in rheumatic diseases.

Authors:  Medya M Shikhagaie; Kristine Germar; Suzanne M Bal; Xavier Romero Ros; Hergen Spits
Journal:  Nat Rev Rheumatol       Date:  2017-02-02       Impact factor: 20.543

2.  Identifying strains that contribute to complex diseases through the study of microbial inheritance.

Authors:  Jeremiah J Faith; Jean-Frédéric Colombel; Jeffrey I Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  2015-01-09       Impact factor: 11.205

Review 3.  Impact of microbes on autoimmune diseases.

Authors:  Claudia Danzer; Jochen Mattner
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2013-02-16       Impact factor: 4.291

Review 4.  Overview of the Genetics of Alcohol Use Disorder.

Authors:  Elisabeth A Tawa; Samuel D Hall; Falk W Lohoff
Journal:  Alcohol Alcohol       Date:  2016-07-21       Impact factor: 2.826

Review 5.  Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications.

Authors:  Adam Cribbs; Marc Feldmann; Udo Oppermann
Journal:  Ther Adv Musculoskelet Dis       Date:  2015-10       Impact factor: 5.346

6.  The heterogeneous human memory CCR6+ T helper-17 populations differ in T-bet and cytokine expression but all activate synovial fibroblasts in an IFNγ-independent manner.

Authors:  Wendy Dankers; Hannah den Braanker; Sandra M J Paulissen; Jan Piet van Hamburg; Nadine Davelaar; Edgar M Colin; Erik Lubberts
Journal:  Arthritis Res Ther       Date:  2021-06-03       Impact factor: 5.156

7.  RAvariome: a genetic risk variants database for rheumatoid arthritis based on assessment of reproducibility between or within human populations.

Authors:  Yoko Nagai; Tadashi Imanishi
Journal:  Database (Oxford)       Date:  2013-10-23       Impact factor: 3.451

8.  Modulation of peripheral T-cell function by interleukin-7 in rheumatoid arthritis.

Authors:  Sarah M Churchman; Jehan J El-Jawhari; Agata N Burska; Rekha Parmar; Vincent Goëb; Philip G Conaghan; Paul Emery; Frederique Ponchel
Journal:  Arthritis Res Ther       Date:  2014-12-23       Impact factor: 5.156

9.  Association of the polymorphisms of TRAF1 (rs10818488) and TNFAIP3 (rs2230926) with rheumatoid arthritis and systemic lupus erythematosus and their relationship to disease activity among Egyptian patients.

Authors:  Mai Moaaz; Nevine Mohannad
Journal:  Cent Eur J Immunol       Date:  2016-07-15       Impact factor: 2.085

Review 10.  Gene expression analysis in RA: towards personalized medicine.

Authors:  A N Burska; K Roget; M Blits; L Soto Gomez; F van de Loo; L D Hazelwood; C L Verweij; A Rowe; G N Goulielmos; L G M van Baarsen; F Ponchel
Journal:  Pharmacogenomics J       Date:  2014-03-04       Impact factor: 3.550
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