Literature DB >> 21600783

Pituitary-ovary-spleen axis in ovulation.

Oliver R Oakley1, Michele L Frazer, CheMyong Ko.   

Abstract

Leukocytes are rapidly recruited to the preovulatory ovary and play a crucial role as facilitators of ovulation and luteal formation. In this article, recent findings on leukocyte trafficking to the ovary, as well as the physiological role of leukocytes in the ovary, will be summarized and discussed. We then explore the novel hypothesis that the hypothalamus-pituitary-ovary (HPO) axis might include the spleen as a reservoir of leukocytes by summarizing recent reports on this topic, both in the fields of immunology and reproductive biology.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21600783      PMCID： PMC3161174          DOI： 10.1016/j.tem.2011.04.005

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  122 in total

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