Literature DB >> 21600511

A modified microsurgical DREZotomy procedure for refractory neuropathic pain.

Hyoung-Joon Chun1, Young Soo Kim, Hyeong-Joong Yi.   

Abstract

OBJECTIVE: Control of neuropathic pain secondary to spinal cord injury is difficult; microsurgical DREZotomy (MDT) is the currently preferred treatment modality. According to previous reports, traditional MDT has poor outcomes when addressing diffuse (infralesional), thermal, and continuous pain. Here, we report improvements in surgical outcomes in these neuropathic pain conditions using a modified MDT technique.
METHODS: Patients with segmental, mechanical, or intermittent pain underwent MDT using the traditional (Sindou's) technique performed at the indicated cord level based on pain distribution. Patients suffering from diffuse, thermal, or continuous pain underwent a modified MDT procedure in the "lump" and "irritative" zones, as well as another procedure, whereby an attempt was made to cut every injured and fused rootlet.
RESULTS: In 38 patients with paraplegic pain resulting from a spinal cord injury occurring within the preceding 7 years, 11 of 15 patients (73%) with a diffuse pain distribution had a good reduction in pain. Thirteen patients (86%) with continuous pain noted good pain relief. In patients with thermal pain, only one patient (20%) demonstrated a good response to the investigational procedure.
CONCLUSION: These procedures, including the modified MDT technique, may be helpful in controlling paraplegic pain in patients suffering from diffuse, thermal, or continuous pain.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21600511     DOI: 10.1016/j.wneu.2010.12.005

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  4 in total

Review 1.  Spinal cord injury pain: mechanisms and management.

Authors:  Nanna Brix Finnerup; Cathrine Baastrup
Journal:  Curr Pain Headache Rep       Date:  2012-06

Review 2.  Neuropathic Pain and Spinal Cord Injury: Phenotypes and Pharmacological Management.

Authors:  Eva Widerström-Noga
Journal:  Drugs       Date:  2017-06       Impact factor: 9.546

3.  Neuropathic pain post spinal cord injury part 2: systematic review of dorsal root entry zone procedure.

Authors:  Swati Mehta; Katherine Orenczuk; Amanda McIntyre; Gabrielle Willems; Dalton L Wolfe; Jane T C Hsieh; Christine Short; Eldon Loh; Robert W Teasell
Journal:  Top Spinal Cord Inj Rehabil       Date:  2013

4.  The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update.

Authors:  Eldon Loh; Magdalena Mirkowski; Alexandria Roa Agudelo; David J Allison; Brooke Benton; Thomas N Bryce; Sara Guilcher; Tara Jeji; Anna Kras-Dupuis; Denise Kreutzwiser; Oda Lanizi; Gary Lee-Tai-Fuy; James W Middleton; Dwight E Moulin; Colleen O'Connell; Steve Orenczuk; Patrick Potter; Christine Short; Robert Teasell; Andrea Townson; Eva Widerström-Noga; Dalton L Wolfe; Nancy Xia; Swati Mehta
Journal:  Spinal Cord       Date:  2022-02-05       Impact factor: 2.473

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.