| Literature DB >> 21600258 |
Hiroyuki Kaiya1, Mikiya Miyazato, Kenji Kangawa.
Abstract
To understand fully the biology of ghrelin, it is important to know the evolutionary history of ghrelin and its receptor. Phylogenetic and comparative genomic studies of mammalian and non-mammalian vertebrates are a useful approach to that end. Ghrelin is a hormone that has apparently evaded natural selection during a long evolutionary history. Surely ghrelin plays crucial physiological roles in living animals. Phylogenetic studies reveal the nature and evolutionary history of this important signaling system.Entities:
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Year: 2011 PMID: 21600258 DOI: 10.1016/j.peptides.2011.04.027
Source DB: PubMed Journal: Peptides ISSN: 0196-9781 Impact factor: 3.750