| Literature DB >> 21598993 |
Weiping Liu1, Xizhu Chen, Qingsong Ye, Yongping Xu, Chengying Xie, Mingjin Xie, Qiaowen Chang, Liguang Lou.
Abstract
A novel water-soluble heptaplatin analogue, cis-[(4R,5R)-4,5-bis-(aminomethyl)-2-isopropyl-1,3-dioxolane](3-hydroxy-1,1-cyclobutanedicarboxylato)platinum(II), has been synthesized and biologically evaluated. The complex shows more activity and less toxicity than its parent drug heptaplatin, exhibiting the great potential for further development.Entities:
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Year: 2011 PMID： 21598993 DOI： 10.1021/ic200436u
Source DB: PubMed Journal: Inorg Chem ISSN： 0020-1669 Impact factor: 5.165