| Literature DB >> 2159855 |
T Hayashi1, K Hayashi, K Uchida, S Niwayama, N Morita.
Abstract
Scopadulcic acid B derivatives were synthesized and their antiviral activities against herpes simplex virus type 1 (HSV-1) were examined. All the derivatives synthesized showed lower inhibitory activities against HSV-1 than scopadulcic acid B (2). Five compounds, 7, 8, 15, 16, and 18, however, had in vitro therapeutic indexes larger than 7 and were considered to merit further investigation.Entities:
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Year: 1990 PMID： 2159855 DOI： 10.1248/cpb.38.239
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645