Literature DB >> 21597472

Fibrocytes: emerging effector cells in chronic inflammation.

Ronald A Reilkoff1, Richard Bucala, Erica L Herzog.   

Abstract

Fibrocytes are mesenchymal cells that arise from monocyte precursors. They are present in injured organs and have both the inflammatory features of macrophages and the tissue remodelling properties of fibroblasts. Chronic inflammatory stimuli mediate the differentiation, trafficking and accumulation of these cells in fibrosing conditions associated with autoimmunity, cardiovascular disease and asthma. This Opinion article discusses the immunological mediators controlling fibrocyte differentiation and recruitment, describes the association of fibrocytes with chronic inflammatory diseases and compares the potential roles of fibrocytes in these disorders with those of macrophages and fibroblasts. It is hoped that this information prompts new opportunities for the study of these unique cells.

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Year:  2011        PMID: 21597472      PMCID: PMC3599774          DOI: 10.1038/nri2990

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN: 1474-1733            Impact factor:   53.106


  89 in total

1.  TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.

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Journal:  Int J Biochem Cell Biol       Date:  2010-10-29       Impact factor: 5.085

2.  Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease.

Authors:  Borna Mehrad; Marie D Burdick; David A Zisman; Michael P Keane; John A Belperio; Robert M Strieter
Journal:  Biochem Biophys Res Commun       Date:  2006-12-11       Impact factor: 3.575

3.  Expression of matrix metalloproteases by fibrocytes: possible role in migration and homing.

Authors:  Carolina García-de-Alba; Carina Becerril; Víctor Ruiz; Yolanda González; Silvia Reyes; Jorge García-Alvarez; Moisés Selman; Annie Pardo
Journal:  Am J Respir Crit Care Med       Date:  2010-07-09       Impact factor: 21.405

4.  Time-course analysis on the differentiation of bone marrow-derived progenitor cells into smooth muscle cells during neointima formation.

Authors:  Jan-Marcus Daniel; Wiebke Bielenberg; Philipp Stieger; Soenke Weinert; Harald Tillmanns; Daniel G Sedding
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-06-24       Impact factor: 8.311

5.  CD34+ fibrocytes in chronic cystitis and noninvasive and invasive urothelial carcinomas of the urinary bladder.

Authors:  Wilhelm Nimphius; Roland Moll; Peter Olbert; Annette Ramaswamy; Peter J Barth
Journal:  Virchows Arch       Date:  2007-02       Impact factor: 4.064

6.  Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.

Authors:  Susan K Mathai; Mridu Gulati; Xueyan Peng; Thomas R Russell; Albert C Shaw; Ami N Rubinowitz; Lynne A Murray; Jonathan M Siner; Danielle E Antin-Ozerkis; Ruth R Montgomery; Ronald A S Reilkoff; Richard J Bucala; Erica L Herzog
Journal:  Lab Invest       Date:  2010-04-19       Impact factor: 5.662

Review 7.  Renal fibrosis: new insights into the pathogenesis and therapeutics.

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Journal:  Kidney Int       Date:  2006-01       Impact factor: 10.612

8.  Semaphorin 7A is a negative regulator of T cell responses.

Authors:  Agnieszka K Czopik; Margaret S Bynoe; Noah Palm; Cedric S Raine; Ruslan Medzhitov
Journal:  Immunity       Date:  2006-05       Impact factor: 31.745

9.  FIZZ1 plays a crucial role in early stage airway remodeling of OVA-induced asthma.

Authors:  Liang Dong; Shu-Juan Wang; Blanca Camoretti-Mercado; Hong-Jia Li; Ming Chen; Wen-Xiang Bi
Journal:  J Asthma       Date:  2008-10       Impact factor: 2.515

10.  C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.

Authors:  Hendrik W van Deventer; Qing Ping Wu; Daniel T Bergstralh; Beckley K Davis; Brian P O'Connor; Jenny P-Y Ting; Jonathan S Serody
Journal:  Am J Pathol       Date:  2008-06-05       Impact factor: 4.307

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  174 in total

Review 1.  Fibrocytes at 20 Years.

Authors:  Rick Bucala
Journal:  Mol Med       Date:  2015-10-27       Impact factor: 6.354

Review 2.  Dendritic cells: novel players in fibrosis and scleroderma.

Authors:  Theresa T Lu
Journal:  Curr Rheumatol Rep       Date:  2012-02       Impact factor: 4.592

Review 3.  Differential macrophage programming in the tumor microenvironment.

Authors:  Brian Ruffell; Nesrine I Affara; Lisa M Coussens
Journal:  Trends Immunol       Date:  2012-01-23       Impact factor: 16.687

4.  Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma.

Authors:  Jeanette A Nimpong; Wintana Gebregziabher; Udai P Singh; Prakash Nagarkatti; Mitzi Nagarkatti; Johnie Hodge; Chunming Liu; Daping Fan; Walden Ai
Journal:  Biochem Biophys Res Commun       Date:  2017-09-01       Impact factor: 3.575

5.  Correlation between circulating fibrocytes and dermal thickness in limited cutaneous systemic sclerosis patients: a pilot study.

Authors:  Barbara Ruaro; Stefano Soldano; Vanessa Smith; Sabrina Paolino; Paola Contini; Paola Montagna; Carmen Pizzorni; Andrea Casabella; Samuele Tardito; Alberto Sulli; Maurizio Cutolo
Journal:  Rheumatol Int       Date:  2019-05-06       Impact factor: 2.631

6.  Immunohistochemical detection of intrathrombotic fibrocytes and its application to thrombus age estimation in murine deep vein thrombosis model.

Authors:  Mizuho Nosaka; Yuko Ishida; Akihiko Kimura; Takashi Kawaguchi; Hiroki Yamamoto; Yumi Kuninaka; Toshikazu Kondo
Journal:  Int J Legal Med       Date:  2016-10-18       Impact factor: 2.686

7.  Fibroblasts secrete Slit2 to inhibit fibrocyte differentiation and fibrosis.

Authors:  Darrell Pilling; Zhichao Zheng; Varsha Vakil; Richard H Gomer
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-08       Impact factor: 11.205

8.  Ultrastructural, ssrDNA sequencing of Myxobolus prochilodus and Myxobolus porofilus and details of the interaction with the host Prochilodus lineatus.

Authors:  Suellen A Zatti; Sarah Arana; Antônio A M Maia; Edson A Adriano
Journal:  Parasitol Res       Date:  2016-09-14       Impact factor: 2.289

Review 9.  Reactive gliosis and the multicellular response to CNS damage and disease.

Authors:  Joshua E Burda; Michael V Sofroniew
Journal:  Neuron       Date:  2014-01-22       Impact factor: 17.173

10.  Peritoneal Dialysis Fluid and Some of Its Components Potentiate Fibrocyte Differentiation.

Authors:  Sarah E Herlihy; Hannah E Starke; Melisa Lopez-Anton; Nehemiah Cox; Katayoon Keyhanian; Donald J Fraser; Richard H Gomer
Journal:  Perit Dial Int       Date:  2015-10-22       Impact factor: 1.756

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