Literature DB >> 21596661

Management of lung cancer-associated anaemia: the Spanish Lung Cancer Anaemia Survey (SLCAS).

Pere Gascón1, José Almenárez, Ángel Artal, Carlos Camps, José Luis Fírvida, Pilar Garrido, José Luis González Larriba, Joaquín Montalar.   

Abstract

BACKGROUND: The purpose of the Spanish Lung Cancer Anaemia Survey (SLCAS) was to thoroughly investigate lung cancer-associated anaemia management, and describe the profile of lung cancer patients in relation to anaemia incidence and tumour type in Spain. PATIENTS AND METHODS: This survey collected data from 1089 randomly recruited patients gathered by 50 Spanish physicians at 38 sites. In addition, a qualitative assay was performed through 16 one-to-one and 2 one-to-two interviews, and a discussion group of 4 cancer specialists participating in the survey.
RESULTS: Lung cancer patients undergoing chemotherapy treatment had haemoglobin (Hb) levels <12.0 g/dl in 58.0% of the cases, in contrast to 39.0% of patients receiving no chemotherapy. Anaemia was treated in 53.0% of patients with Hb<12 g/dl (45.0% epoetin, 3.9% transfusion, 4.1% iron). Mean Hb level trigger was 9.7 g/dl for administration of epoetin and 8.2 g/dl for blood transfusion.
CONCLUSIONS: SLCAS reveals a significant change in the management of anaemia and clinical practice pattern in the use of erythropoiesis-stimulating agents (45.0% vs. 18.0%) and much less use of blood transfusions (3.9% vs. 15.0%) since the European Cancer Anaemia Survey performed five years ago.

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Year:  2011        PMID: 21596661     DOI: 10.1007/s12094-011-0662-5

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  22 in total

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2.  Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review.

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Journal:  Cancer       Date:  2001-06-15       Impact factor: 6.860

3.  Toxicity and response criteria of the Eastern Cooperative Oncology Group.

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Review 4.  EORTC guidelines for the use of erythropoietic proteins in anaemic patients with cancer: 2006 update.

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Review 5.  The impact of anaemia on outcome in cancer.

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Review 9.  Impact of haemoglobin levels on the outcome of cancers treated with chemotherapy.

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10.  Independent risk factors for anemia in cancer patients receiving chemotherapy: results from the European Cancer Anaemia Survey.

Authors:  Peter J Barrett-Lee; Heinz Ludwig; Gunnar Birgegård; Carsten Bokemeyer; Pere Gascón; Paris A Kosmidis; Maciej Krzakowski; Johan W R Nortier; Gail Kongable; Maurice Schneider; Dirk Schrijvers; Simon J Van Belle
Journal:  Oncology       Date:  2006-02-21       Impact factor: 2.935

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